QIAGEN Transfers Distribution Rights for Transp...
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Transaction allows QIAGEN to increase focus on personalized medicine
applications of HLA testing products
VENLO, The Netherlands, June 16, 2009 - QIAGEN N.V. (NASDAQ: QGEN;
Frankfurt, Prime Standard: QIA) today announced that it has signed an
agreement to transfer distribution rights on July 1, 2009 for the
Olerup SSP® product line and the related assets to Olerup
International AB, a subsidiary of LinkMed (NASDAQ OMX Nordic
Exchange: LMED), a Swedish venture capital company specializing in
Life Sciences.
The Olerup SSP® product line includes molecular transplantation
testing products used for DNA HLA typing. QIAGEN will retain rights
to all Olerup SSP® assays for applications outside transplantation
testing, such as in personalized medicine. The transaction does not
affect QIAGEN's presence in new sequencing-based typing assays in the
area of transplantation. As part of the transaction, QIAGEN will
transfer all assets related to its Olerup SSP® HLA sales
infrastructure to LinkMed, including office infrastructure in
Austria. LinkMed will assume this office's staff of eight employees.
Through this transaction, QIAGEN is increasing its focus on the
higher growth applications in transplantation testing such as
sequencing-based typing, as well as the application of such assays in
personalized medicine.
Human leukocyte antigens (HLA) are molecules found on cell surfaces
that regulate how the body recognizes and thus possibly rejects
foreign tissue transplants. Molecular profiling of HLA sequences, or
"Typing", is typically performed prior to organ or bone marrow
transplantations: the better the HLA match between a donor and a
recipient, the lower the risk for transplantation-related
complications, such as graft versus host disease, where the body
rejects the transplant. The products QIAGEN covered in this
distribution rights transfer agreement are the sequence specific
primer ("SSP") typing products for determining HLA alleles using PCR
techniques with SSP. The SSP technology was added to QIAGEN's product
portfolio in 2002 as part of the acquisition of GenoVision.
Historically, these products have been sold at a lower margin than
QIAGEN's average molecular diagnostic assays and have been focused on
certain niche market segments only. Going forward, QIAGEN will focus
on the commercialization of its new SBTexcellerator kits from its
alliance with Genome Diagnostics N.V. In contrast to SSP, the
SBTexcellerator product line, which was completed in March 2009, uses
another advanced HLA typing technology, known as "Sequencing-Based
Typing" (SBT).
According to the agreement, QIAGEN will continue to have distribution
rights to Olerup SSP® products that can be used in applications
outside transplantation testing, such as the rapidly emerging use of
such products in personalized medicine. Such tests include, among
others, the typing of the HLA-B*5701 allele - a test to assess the
risk of AIDS patients for severe adverse reactions to the widely
prescribed HIV drug component Abacavir. The agreement also includes
options for QIAGEN to distribute future Olerup SSP® assays for
pharmacogenetic applications.
"This transaction gives us the chance to quickly jump-start sales of
a well-established product-line that seamlessly fits into our overall
offering", said Ingemar Lagerlöf, CEO of LinkMed, which had acquired
the research and production parts of the Olerup SSP® business in
2008. Recently, LinkMed has established Olerup International AB for
future distribution of its SSP products.
"The agreement with LinkMed allows us to further execute our
corporate strategy and streamline our portfolio. We focus on the
development and commercialization of innovative sample and assay
technologies for molecular diagnostics, which are strongly driven by
the emergence of personalized medicine", said Peer M. Schatz, CEO of
QIAGEN. "HLA assays are expected to play a key role in personalized
medicine as evidenced by recent developments and research. Through
our new arrangement, we can increase our focus on a portfolio of
HLA-related products for use in the high growth area of personalized
medicine."
The transfer of the Olerup SSP® product line does not impose any
changes in ordering processing for HLA customers using
SBTexcellerator kits. QIAGEN's life science and diagnostics customers
in Austria will be served by the German sales organization, while
customers in Turkey continue to order all SSP kits via QIAGEN's local
sales office ATQ.
The transaction is expected to reduce QIAGEN's revenues in the second
half of 2009 by approximately US$10 million but will neither impact
the company's expected adjusted earnings per share for full year 2009
nor future expected earnings.
About QIAGEN:
QIAGEN N.V., a Netherlands holding company, is the
leading global provider of sample and assay technologies. Sample
technologies are used to isolate and process DNA, RNA and proteins
from biological samples such as blood or tissue. Assay technologies
are used to make such isolated biomolecules visible. QIAGEN has
developed and markets more than 500 consumable products as well as
automated solutions for such consumables. The company provides its
products to molecular diagnostics laboratories, academic researchers,
pharmaceutical and biotechnology companies, and applied
testing customers for purposes such as forensics, animal or food
testing and pharmaceutical process control. QIAGEN's assay
technologies include one of the broadest panels of molecular
diagnostic tests available worldwide. This panel includes the digene
HPV Test, which is regarded as the "gold standard" in testing for
high-risk types of human papillomavirus (HPV), the primary cause of
cervical cancer. QIAGEN employs more than 3,100 people in over 30
locations worldwide. Further information about QIAGEN can be found at
http://www.qiagen.com/.
About LinkMed:
LinkMed develops life science companies in collaboration with
innovators and other financiers. By contributing management and
capital, LinkMed has created a portfolio of twelve companies, four in
drug development and biotechnology and eight in diagnostics and
medical technology. LinkMed is listed on the NASDAQ OMX Nordic
Exchange in the Small Cap section (ticker: LMED). In 2008, LinkMed
has acquired Olerup SSP AB, a leading producer of SSP-based human
leukocyte antigen (HLA) tissue typing kits and reagents. Olerup SSP's
products are sold world-wide to tissue typing laboratories, national
bone marrow donor registries and other laboratories. Within the
segment PCR-SSP, management estimates Olerup SSP to be the global
leader in relation to HLA. Olerup SSP AB is a wholly owned subsidiary
of LinkMed. Olerup International AB owned by LinkMed and SSP Primers
AB will from now on handle distribution and sales of Olerup SSP
products.
Statements contained in this release that are not historical facts
are forward-looking statements, including statements about our
products, markets, strategy and operating results. Such statements
are based on current expectations that involve risks and
uncertainties including, but not limited to, those associated with:
management of growth and international operations (including currency
fluctuations and logistics), variability of our operating results,
commercial development of our markets (including applied testing,
clinical and academic research, proteomics, women's health/HPV
testing and molecular diagnostics), our relationships with customers,
suppliers and strategic partners, competition, changes in technology,
fluctuations in demand, regulatory requirements, identifying,
developing and producing integrated products differentiated from our
competitors' products, market acceptance of our products, and
integration of acquired technologies and businesses. For further
information, refer to our filings with the SEC, including our latest
Form 20-F. Information in this release is as of the date of the
release, and we undertake no duty to update this information unless
required by law.
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Qiagen N.V.
Spoorstraat 50 KJ Venlo Netherlands
WKN: 901626; ISIN:
NL0000240000; Index: HDAX, MIDCAP, Prime All Share, TECH All Share,
TecDAX;
Listed: Prime Standard in Frankfurter Wertpapierbörse, Freiverkehr in
Börse Berlin,
Freiverkehr in Börse Düsseldorf, Freiverkehr in Hanseatische
Wertpapierbörse zu Hamburg,
Freiverkehr in Niedersächsische Börse zu Hannover, Freiverkehr in
Bayerische Börse München,
Freiverkehr in Börse Stuttgart;