Director/PDMR Shareholding

ReNeuron Group plc
08 August 2007


NOTIFICATION OF TRANSACTIONS OF DIRECTORS, 
PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY OR CONNECTED PERSONS


This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).

(1)     An issuer making a notification in respect of a transaction 
        relating to the shares or debentures of the issuer should complete
        boxes 1 to 16, 23 and 24.
(2)     An issuer making a notification in respect of a derivative relating 
        to the shares of the issuer should complete boxes 1 to 4, 6, 8, 13, 14, 
        16, 23 and 24. 
(3)     An issuer making a notification in respect of options granted to a 
        director/person discharging managerial responsibilities should 
        complete boxes 1 to 3 and 17 to 24. 
(4)     An issuer making a notification in respect of a financial 
        instrument relating to the shares of the issuer (other than a 
        debenture) should complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 
        23 and 24. 


Please complete all relevant boxes in block capital letters.

1.   Name of the issuer   
           
     RENEURON GROUP PLC

2.   State whether the notification relates to (i) a transaction 
     notified in accordance with DR 3.1.4R(1)(a); or

     (ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 
     (as extended by section 328) of the Companies Act 1985; or 

     (iii) both (i) and (ii)

     A TRANSACTION NOTIFIED IN ACCORDANCE WITH DR 3.1.4R(1)(A).

3.   Name of person discharging managerial responsibilities/director  

     JOHN SINDEN - DIRECTOR
        
4.   State whether notification relates to a person connected with a person
     discharging managerial responsibilities/director named in 3 and identify 
     the connected person
 

        
5.   Indicate whether the notification is in respect of a holding of the person 
     referred to in 3 or 4 above or in respect of a non-beneficial interest(1)      



6.   Description of shares (including class), debentures or derivatives or 
     financial instruments relating to shares


               
7.   Name of registered shareholders(s) and, if more than one, the number of
     shares held by each of them   



8.   State the nature of the transaction
               


9.   Number of shares, debentures or financial instruments relating to shares 
     acquired 



10.  Percentage of issued class acquired (treasury shares of that class should 
     not be taken into account when calculating percentage)


               
11.  Number of shares, debentures or financial instruments relating to shares
     disposed     



12.  Percentage of issued class disposed (treasury shares of that class should
     not be taken into account when calculating percentage) 


               
13.  Price per share or value of transaction    



14.  Date and place of transaction

               

15.  Total holding following notification and total percentage holding following 
     notification (any treasury shares should not be taken into account when 
     calculating percentage)   



16.  Date issuer informed of transaction

               

If a person discharging managerial responsibilities has been granted options by 
the issuer complete the following boxes


17.  Date of grant   

     7 AUGUST 2007

18.  Period during which or date on which it can be exercised

     10 YEARS FROM THE 7 AUGUST 2007 SUBJECT TO PERFORMANCE CONDITIONS

19.  Total amount paid (if any) for grant of the option  

     NIL

20.  Description of shares or debentures involved (class and number)

     1,000,000 ORDINARY SHARES
               
21.  Exercise price (if fixed at time of grant) or indication that price is 
     to be fixed at the time of exercise     

     500,000 ORDINARY SHARES AT AN EXERCISE PRICE OF 21 PENCE PER SHARE; AND

     500,000 ORDINARY SHARES AT AN EXERCISE PRICE OF 37.5 PENCE PER SHARE.

22.  Total number of shares or debentures over which options held following 
     notification
               
     3,396,680 ORDINARY SHARES

     (INCLUDING ALL PREVIOUS OPTIONS)


23.  Any additional information  

     GRANTED UNDER THE RULES OF THE EMPLOYEE SHARE OPTION SCHEME

24.  Name of contact and telephone number for queries

     MICHAEL HUNT
     CHIEF EXECUTIVE OFFICER
     PH: [phone]
               

Name and signature of duly authorised officer of issuer responsible for 
making notification



Date of notification      8/8/07






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