Director/PDMR Shareholding

ReNeuron Group plc
07 December 2006


                            Director Share Purchases

Guildford, UK, 6 December 2006: ReNeuron Group plc (LSE: RENE) today announces
the following purchases of ordinary shares in ReNeuron by directors of the
Company at 19.5p per share.


Name                               Number of Shares Purchased

Michael Hunt                       51500
John Sinden                        36000
Mark Docherty                      51400(1)
Trevor Jones                       25700
Paul Harper                        57500



Following these purchases the directors of ReNeuron have the following interests
in issued ordinary shares in ReNeuron:


Name                              Number of shares           Percentage of issued share
                                                             capital
Michael Hunt                      174,613                    0.18%
John Sinden                       1,219,925(2)               1.22%
Mark Docherty                     146,400(3)                 0.15%
Trevor Jones                      83,200                     0.08%
Paul Harper                       83,200                     0.08%





The current issued ordinary share capital of the Company is 99,604,700 shares.



(1) = including 24,700 ordinary shares acquired by the MD FURBS, a funded
      unapproved retirement benefit scheme established by Mark Docherty

(2) = in addition John Sinden holds 117,160 ordinary shares on trust for
      family members

(3) = including 120,700 ordinary shares held by the MD FURBS, a funded
      unapproved retirement benefit scheme established by Mark Docherty


                                      ENDS


Enquiries:


ReNeuron
Michael Hunt, CEO                                    Tel: [phone]
John Sinden, CSO

Financial Dynamics
David Yates                                          Tel: [phone]
Nicola Daley




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