Grant-funded collaboration with exosome platform

RNS Number : 9930I

ReNeuron Group plc

14 August 2019

 

 

14 August 2019

AIM: RENE

ReNeuron Group plc

("ReNeuron" or "the Company")

Grant-funded collaboration with exosome platform

ReNeuron Group plc (AIM: RENE), a UK-based global leader in the development of cell-based therapeutics, is pleased to announce that it is partnering with the University of Cardiff under a new grant-funded collaboration utilising ReNeuron's exosome-based drug delivery technology platform.

The grant has been awarded under Innovate UK's Knowledge Transfer Partnership and will fund a £250,000 collaborative programme of research to be undertaken by ReNeuron and the European Cancer Stem Cell Research Institute at Cardiff University.  The research programme will develop novel systems to enable the delivery of therapeutic nucleic acids, such as small interfering RNA (siRNA), across the blood brain barrier using ReNeuron's CTX stem cell-derived exosomes.

Delivering therapeutic compounds across the blood brain barrier remains a significant challenge - current delivery methods focus on easier-to-reach areas of the body.  Earlier data generated at ReNeuron have already demonstrated the ability of its CTX-derived exosomes to cross the blood brain barrier.  The ambition of the collaboration between ReNeuron and the University of Cardiff is to open up a new route for the delivery of therapeutic agents that have previously failed to target the brain.

Commenting on the grant award, Dr Randolph Corteling, Head of Research at ReNeuron, commented:

"We and our collaborators are delighted to have won this latest grant from Innovate UK.  We are very excited about the potential of our exosome technology platform to deliver therapeutic compounds to the brain and thereby to make a real step-change in the development of treatments against hard-to-target disorders of the central nervous system."

ENDS

Enquiries:

ReNeuron	[phone]
Olav Hellebø, Chief Executive Officer
Michael Hunt, Chief Financial Officer
Buchanan	[phone]
Mark Court, Sophie Wills, Tilly Abraham
Stifel Nicolaus Europe Limited Jonathan Senior, Stewart Wallace, Ben Maddison (NOMAD and Joint Broker)	[phone]
N+1 Singer Aubrey Powell, James Moat, Iqra Amin (Joint Broker)	[phone]

About ReNeuron

ReNeuron is a global leader in cell-based therapeutics, harnessing its unique stem cell technologies to develop 'off the shelf' stem cell treatments, without the need for immunosuppressive drugs.  The Company's lead clinical-stage candidates are in development for the blindness-causing disease, retinitis pigmentosa and for disability as a result of stroke.  ReNeuron is also advancing its proprietary exosome technology platform as a potential delivery system for drugs that would otherwise be unable to reach their site of action.  ReNeuron's shares are traded on the London AIM market under the symbol RENE.L. Further information on ReNeuron can be found at www.reneuron.com.

 

END

 

 

MSCGUGDISXBBGCS