Regulatory Update

ReNeuron Group plc
09 January 2007

                               Regulatory Update



Guildford, UK, 9 January 2007: ReNeuron Group plc (LSE: RENE) today provides an
update regarding its recently filed Investigational New Drug (IND) application
to commence a Phase I clinical study for its ReN001 stem cell therapy for
stroke.  The US Food and Drug Administration (FDA) has orally confirmed that it
has placed the proposed clinical study on hold.  A telephone conference call
with the FDA to discuss the application is expected to take place later this
week, following which the Company will make a further announcement.



Michael Hunt, Chief Executive Officer of ReNeuron, said:



 'We are encouraged to be able to engage in an immediate dialogue with the FDA
regarding our IND application, now that the initial review process has taken
place.  Given the ground-breaking nature of our ReN001 therapy and the lack of
comparable approaches addressing stroke, it is not surprising that the FDA might
wish to raise questions or make comments at this point in the approval process.
We look forward to a constructive dialogue with the FDA and, in the meantime, we
continue with our ongoing preparations for the initial ReN001 clinical study.'





Enquiries:


ReNeuron
Michael Hunt, CEO                                    Tel: [phone]


Financial Dynamics
David Yates                                          Tel: [phone]
Nicola Daley





Notes to Editors



ReNeuron is a leading, UK-based adult stem cell therapy business.  It is
applying its novel stem cell platform technologies in the development of
ground-breaking stem cell therapies to serve significant and unmet or poorly-met
clinical needs.



ReNeuron has used its c-mycERTAM technology to generate genetically stable
neural stem cell lines.  This technology platform has multi-national patent
protection and is fully regulated by means of a chemically-induced safety
switch.  Cell growth can therefore be completely arrested prior to in vivo
implantation.



ReNeuron has filed for approval to commence initial clinical studies in the US
with its lead ReN001 stem cell therapy for chronic stroke disability.  This
represents the world's first such filing concerning a neural stem cell treatment
for a major neurological disorder.  There are an estimated 50 million stroke
survivors worldwide, approximately one half of which are left with permanent
disabilities.  The annual health and social costs of caring for these patients
is estimated to be in excess of £5 billion in the UK and in excess of US$50
billion in the US.



ReNeuron has also generated pre-clinical efficacy data with its ReN005 stem cell
therapy for Huntington's disease, a genetic and fatal neurodegenerative disorder
that affects around 1 in 10,000 people.  This programme is in pre-clinical
development.



In addition to its stroke and Huntington's disease programmes, ReNeuron is
developing stem cell therapies for Parkinson's disease, Type 1 diabetes and
diseases of the retina.



ReNeuron has also leveraged its stem cell technologies into non-therapeutic
areas - its ReNcellTM range of cell lines for use in research and in drug
discovery applications in the pharmaceutical industry.  ReNeuron's ReNcellTM CX
and ReNcellTM VM neural cell lines are marketed worldwide under license by
Millipore Corporation.



ReNeuron's shares are traded on the London AIM market under the symbol RENE.L.



Further information on ReNeuron and its products can be found at
www.reneuron.com.



Data sources: UK Stroke Association, American Stroke Association.



This announcement contains forward-looking statements with respect to the
financial condition, results of operations and business achievements/performance
of ReNeuron and certain of the plans and objectives of management of ReNeuron
with respect thereto. These statements may generally, but not always, be
identified by the use of words such as 'should', 'expects', 'estimates',
'believes' or similar expressions. This announcement also contains
forward-looking statements attributed to certain third parties relating to their
estimates regarding the growth of markets and demand for products. By their
nature, forward-looking statements involve risk and uncertainty because they
reflect ReNeuron's current expectations and assumptions as to future events and
circumstances that may not prove accurate.  A number of factors could cause
ReNeuron's actual financial condition, results of operations and business
achievements/performance to differ materially from the estimates made or implied
in such forward-looking statements and, accordingly, reliance should not be
placed on such statements.



The terms 'ReNeuron', 'the Company' or 'the Group' used in this statement refer
to ReNeuron Group plc and/or its subsidiary undertakings, depending on the
context.




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