Holding(s) in Company

Aortech International PLC
04 June 2003


AorTech International plc ('the Company') announces that it received
notification today from ISIS Asset Management plc that ISIS Asset Management plc
has a revised notifiable interest in 7,082,986 Ordinary Shares in the Company
representing approximately 18.59% of the issued ordinary share capital.

Such interest includes the material interests of the clients of ISIS Asset
Management plc referred to below:


Name of Client                                No. of Shares          %         Name of Registered Holder

Baronsmead VCT2                               162,341                0.43      Chase Nominees Ltd
Baronsmead VCT Plc                            127,341                0.33      Chase Nominees Ltd
The AIM Trust Plc                             2,113,409              5.54      Chase Nominees Ltd
The AIM VCT Trust                             509,806                1.34      Chase Nominees Ltd
3PC Investment Trust                          1,997,872              5.24      Chase Nominees Ltd



Such interest also includes the interest of Friends Provident Unit Managers
which is also a member of the Friends Provident group as referred to below:


Name of Client                                No. of Shares          %         Name of Registered Holder

ISIS ICVC Aim Growth Fund                     75,000                 0.20      Citifriends
ISIS ICVC UK Smaller Markets Fund             167,524                0.44      Citifriends


Name of Client                                No. of Shares          %         Name of Registered Holder

FP UK Equity Fund                             93,831                 0.25      Citifriends
FIS UK Mid/Smaller Companies                  1,672,452              4.39      Citifriends


Such interest includes the material interest of the client of ISIS Managed
Pension Funds referred to below:


Name of Client                                No. of Shares          %         Name of Registered Holder

ISISMPF UK Smaller Companies                  163,410                0.43      Citifriends


In addition, ISIS Asset Management plc, as the holding company of the company(s)
referred to in the paragraph(s) above is also interested in those Shares.
Furthermore, Friends Provident Life Office, as the holding company of ISIS Asset
Management plc is also interested in the Shares referred to above.



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