Holding(s) in Company

Aortech International PLC
06 June 2003



AorTech International plc ('the Company') announces that:

(1)     it received notification yesterday from ISIS Asset Management
        plc that ISIS Asset Management plc has a revised notifiable interest in
        7,682,986 Ordinary Shares in the Company representing approximately
        20.164% of the issued ordinary share capital.

        Such interest includes the material interests of the clients of ISIS
        Asset Management plc referred to below:


Name of Client                            No. of Shares       %            Name of Registered Holder

Baronsmead VCT2                           162,341             0.426        Chase Nominees Ltd
Baronsmead VCT Plc                        127,341             0.334        Chase Nominees Ltd
The AIM Trust Plc                         2,113,409           5.547        Chase Nominees Ltd
The AIM VCT Trust                         509,806             1.338        Chase Nominees Ltd
3PC Investment Trust                      2,597,872           6,818        Chase Nominees Ltd


Such interest also includes the interest of Friends Provident Unit
Managers which is also a member of the Friends Provident group referred
to below:

Name of Client                            No. of Shares       %            Name of Registered Holder

ISIS ICVC Aim Growth Fund                 75,000              0.197        Citifriends
ISIS ICVC UK Smaller Markets Fund         167,524             0.440        Citifriends


Name of Client                            No. of Shares       %            Name of Registered Holder

FP UK Equity Fund                         93,831              0.246        Citifriends
FIS UK Mid/Smaller Companies              1,672,452           4.389        Citifriends


Such interest includes the material interest of the client of ISIS
Managed Pension Funds referred to below:

Name of Client                            No. of Shares       %            Name of Registered Holder

ISISMPF UK Smaller Companies              163,410             0.429        Citifriends


In addition, ISIS Asset Management plc, as the holding company of the
company(s) referred to in the paragraph(s) above is also interested in
those Shares. Furthermore, Friends Provident Life Office, as the holding
company of ISIS Asset Management plc is also interested in the Shares
referred to above.



(2)     it received notification yesterday that Erudite Ltd, a UK
        company owned by Peter Gyllenhammar, has acquired 750,000 Ordinary
        Shares in the Company which increases his beneficial interest to
        4,489,177 Ordinary Shares representing approximately 11.78% of the
        issued Ordinary Share Capital.



(3)     it also received notification yesterday from James Sharp & Co
        that David Barry and Value Investments Limited no longer have a
        notifiable interest in the issued Ordinary Share capital of the Company.




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