Holding(s) in Company

Aortech International PLC
06 May 2004

6 May 2004



                           AorTech International plc

AorTech International plc ('the Company') announces that it received
notification today from ISIS Asset Management plc that as a result of a purchase
of 181,704 ordinary shares of 250p each in the capital of the Company ('Shares')
on 5 May 2004, the following fund management companies in the Friends Provident
group are interested in the Shares referred to below through client holdings:

ISIS Asset Management plc is interested in the following Shares:

No. of Shares                                               %
950,000                                                     24.93

Such interest includes the material interests of the clients of ISIS Asset
Management plc referred to below:

Name of Client           No. of Shares        %        Name of Registered Holder
Active Capital Trust           861,861        22.62    Chase Nominees Ltd

In addition, ISIS Asset Management plc, as the holding company of the company(s)
referred to in the paragraph(s) above is also interested in those Shares.
Furthermore, Friends Provident Life Office, as the holding company of ISIS Asset
Management plc is also interested in the Shares referred to above.


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