Holding(s) in Company

Aortech International PLC 28 February 2008 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached (ii): AorTech International plc 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: (Yes ) An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify): ( ) 3. Full name of person(s) subject to the notification obligation (iii): Credit Agricole Cheuvreux International Ltd 4. Full name of shareholder(s) (if different from 3.) (iv): Credit Agricole Cheuvreux International Ltd 5. Date of the transaction (and date on which the threshold is crossed or reached if different) (v): 25 February 2008 6. Date on which issuer notified: 27 February 2008 7. Threshold(s) that is/are crossed or reached: Less than 3% 8. Notified details: A: Voting rights attached to shares Class/type of shares Situation previous to the Triggering transaction if possible using (vi) the ISIN CODE Number of shares Number of voting Rights (viii) GB0033360586 372,500 372,500 Resulting situation after the triggering transaction (vii) Class/type of Number of Number of voting % of voting rights shares if shares rights (ix) possible using the ISIN CODE Direct Indirect Direct Indirect (x) (xi) GB0033360586 Less than 3% B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of Expiration Date Exercise/Conversion Number of voting % of voting financial (xiii) Period/Date (xiv) rights that may be rights instrument acquired if the instrument is exercised/ converted. N/A N/A N/A N/A N/A Total (A+B) Number of voting rights % of voting rights Less than 3% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable (xv): SAS Rue La Boetie Credit Agricole SA Calyon SA Credit Agricole Cheuvreux SA Less than 3% Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: Gabrielle Burne 15. Contact number: 020 7214 6037 Annex to Notification Of Major Interests In Shares (xvi) A: Identity of the person or legal entity subject to the notification obligation Full name (including legal form for legal entities): Credit Agricole SA Contact address (registered office for legal entities): Broadwalk House, 5 Appold Street, London EC2A 2DA Phone number: 020 7214 6037 Other useful information (at least legal representative for legal persons): B: Identity of the notifier, if applicable (xvii) Full name: Barbara Hall Contact address: As above Phone number: As above Other useful information (e.g. functional relationship with the person or legal entity subject to the notification obligation) n/a This information is provided by RNS The company news service from the London Stock Exchange
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