Holding(s) in Company

Aortech International PLC
13 February 2008


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):

   AorTech International plc

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: (Yes )
   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )
   An event changing the breakdown of voting rights: ( )
   Other (please specify): ( )

3. Full name of person(s) subject to the notification obligation (iii):

   Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):

   Credit Agricole Cheuvreux International Ltd

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):

   6 February 2008

6. Date on which issuer notified:

   8 February 2008

7. Threshold(s) that is/are crossed or reached:

   8%

8. Notified details:



A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction
if possible using                          (vi)
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0033360586              Less than 3%                    Less than 3%


Resulting situation after the triggering transaction (vii) Less than 3%

Class/type of           Number of      Number of voting    % of voting rights
shares if                  shares           rights (ix)
possible using
the ISIN CODE
                          Direct    Direct    Indirect     Direct Indirect
                                       (x)        (xi)
GB0033360586             427,500   427,500           -      8.85%        -

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
N/A         N/A              N/A                 N/A                   N/A


Total (A+B)
 Number of voting rights  % of voting rights
                 427,500               8.85%


9. Chain of controlled undertakings through which the voting rights and/or the
   financial instruments are effectively held, if applicable (xv):

   SAS Rue La Boetie
   Credit Agricole SA
   Calyon SA
   Credit Agricole Cheuvreux SA 427,500 (8.85%)


Proxy Voting:

10. Name of the proxy holder:


11. Number of voting rights proxy holder will cease to hold:


12. Date on which proxy holder will cease to hold voting rights:


13. Additional information:


14. Contact name:

    Gabrielle Burne

15. Contact number:

    020 7214 6037



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