Shareholding

Sareum Holdings PLC
03 December 2004


For Immediate Release                                            3 December 2004





                              SAREUM HOLDINGS PLC

                          ("Sareum" or the "Company")



                         Ordinary Shares of 0.025 pence

Sareum Holdings plc (AIM: SAR), the structure-based drug discovery and services
business, was notified on 3rd December, 2004, that Billam AG purchased on 3rd
December a total of 5,700,000 Ordinary Shares and now holds, together with its
directors Peter Hoskins and Jemima Thorpe, 18,050,000 Ordinary Shares
representing 5.2 per cent. of the issued share capital of the Company.

For further information contact:


Sareum Ltd                                                  [phone]

Tim Mitchell, Chief Executive Officer

Buchanan Communications                                     [phone]

Mark Court, Mary-Jane Johnson





                      This information is provided by RNS
            The company news service from the London Stock Exchange