Holding(s) in Company

Smith & Nephew Plc
17 December 2004


                                   SCHEDULE 10
          
                    NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Name of company

SMITH & NEPHEW PLC


2. Name of shareholder having a major interest

FMR Corp and Fidelity International Limited


3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Non-beneficial interest


4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

Master Trust Bank of Japan   65,400
Bank of New York Brussels   60,800
Brown Brothers Harriman Ltd LUX  584,622
JP Morgan Bournemouth   12,470
State Street Bank & Trust Company London   82,142
JP Morgan Bournemouth   993,102
Brown Brothers Harriman & Co  23,432,767
JP Morgan Chase Bank  22,278,705
State Street Bank & Trust Company   2,723,460
Mellon Bank N.A.  8,460
State Street Bank & Trust Company   620,800
Fidelity Investments International  853,900
Bank of New York Brussels   1,298,366
Bankers Trust London  218,427
Citibank 203,754
Clydesdale Bank plc   96,500
JP Morgan Bournemouth   507,400
Mellon Bank   561,575
Midland Securities Services   109,727
Northern Trust London   1,193,126
State Street Bank & Trust Company London   281,300


The following shares are from the assumed conversion of 642,550 ADRs (5 ordinary 
shares per ADR):

HSBC   642,500
JP Morgan Chase   50


5. Number of shares / amount of stock acquired




6. Percentage of issued class




7. Number of shares / amount of stock disposed

8,655,287


8. Percentage of issued class

0.92%


9. Class of security

Ordinary Shares of 12 2/9p


10. Date of transaction

15.12.2004


11. Date company informed

17.12.2004


12. Total holding following this notification

56,829,353


13. Total percentage holding of issued class following this notification

6.06%


14. Any additional information




15. Name of contact and telephone number for queries

Kate Cummins - Company Secretarial Assistant
0207 960 2251


16. Name and signature of authorised company official responsible for making
this notification

Phil Higgins - Assistant Company Secretary


Date of notification

17.12.2004


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for loss of business or loss of profits) arising in contract, tort or otherwise
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it, or from any action or decision taken as a result of using this document or
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