Major Interests in Shares

Smiths Group PLC
04 December 2006

4 DECEMBER 2006

NOTIFICATION OF MAJOR INTERESTS IN SHARES

LISTING RULE LR 9.6.7 R

1.      Name of listed company: SMITHS GROUP PLC

2.      Name of shareholder with a major interest: BARCLAYS PLC

3.      Please state whether notification indicates that it is regarding the
        holding of the shareholder named in 2 above; in respect of a 
        non-beneficial interest; or in the case of an individual holder if it is 
        a holding of that person's spouse or children under the age of 18

NOTIFICATION BY BARCLAYS PLC OF A NOTIFIABLE INTEREST THROUGH THE LEGAL ENTITIES:

BARCLAYS BANK TRUST COMPANY LTD;
BARCLAYS CAPITAL INC.;
BARCLAYS CAPITAL SECURITIES LTD;
BARCLAYS GLOBAL FUND ADVISORS;
BARCLAYS GLOBAL INVESTORS AUSTRALIA LTD;
BARCLAYS GLOBAL INVESTORS CANADA LTD;
BARCLAYS GLOBAL INVESTORS LTD;
BARCLAYS GLOBAL INVESTORS, N.A.;
BARCLAYS GLOBAL INVESTORS JAPAN LTD;
BARCLAYS GLOBAL INVESTORS JAPAN TRUST & BANKING;
BARCLAYS LIFE ASSURANCE CO LTD;
BARCLAYS PRIVATE BANK AND TRUST LTD;
BARCLAYS PRIVATE BANK LTD; AND
GERRARD LTD


4.  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them

Registered holder                                                         Shares
Bank of New York                                                          40,331
Barclays Capital Nominees Ltd                                          8,052,824
Barclays Trust Co as Exec/Adm C                                                6
Barclays Global Investors Canada                                          42,996
Barclays Trust Co & Others                                                 3,750
Barclays Trust Co DMC69                                                   11,500
Barclays Trust Co E99                                                        251
Barclays Trust Co R69                                                     60,262
Chase Nominees Ltd 16376 a/c                                             287,004
Chase Nominees Ltd 28270 a/c                                             191,421
Clydesdale Nominees HGB0125                            32349601 a/c        1,689
Clydesdale Nominees HGB0125                            32449201 a/c        4,929
Clydesdale Nominees HGB0125                            59419801 a/c          311
Clydesdale Nominees HGB0125                            59553401 a/c        1,155
Clydesdale Nominees HGB0125                            59571201 a/c          478
Clydesdale Nominees HGB0125                            59710301 a/c          455
Clydesdale Nominees HGB0125                            59732401 a/c        1,633
Clydesdale Nominees HGB0125                            59737501 a/c        1,450
Clydesdale Nominees HGB0125                            59738301 a/c        1,898
Clydesdale Nominees HGB0125                            59744801 a/c          925
Clydesdale Nominees HGB0125                            64544201 a/c        1,288
Clydesdale Nominees HGB0125                            65136101 a/c          519
Clydesdale Nominees HGB0125                            66860401 a/c          412
Clydesdale Nominees HGB0125                            67940101 a/c        6,968
Clydesdale Nominees HGB0125                            69108801 a/c          750
Clydesdale Nominees HGB0125                            69238601 a/c        1,713
Clydesdale Nominees HGB0125                            69340401 a/c          750
Clydesdale Nominees HGB0125                            69732901 a/c        5,352
Clydesdale Nominees HGB0125                            69738801 a/c          501
Clydesdale Nominees HGB0125                            69829501 a/c          823
Clydesdale Nominees HGB0125                            70314001 a/c          477
Clydesdale Nominees HGB0125                            70335301 a/c          992
Clydesdale Nominees HGB0125                            70339601 a/c          623
Clydesdale Nominees HGB0125                            70387601 a/c          502
Clydesdale Nominees HGB0125                            70388401 a/c          691
Clydesdale Nominees HGB0125                            70391401 a/c          407
Clydesdale Nominees HGB0125                            80750701 a/c        2,900
Clydesdale Nominees HGB0125                            80766301 a/c          611
Clydesdale Nominees HGB0125                            83011801 a/c          735
Clydesdale Nominees HGB0125                            86680501 a/c          656
Clydesdale Nominees HGB0125                            88608301 a/c          557
Clydesdale Nominees HGB0125                            120142001 a/c       4,800
Clydesdale Nominees HGB0125                            300000001 a/c         628
Clydesdale Nominees HGB0125                            310007101 a/c       1,222
Clydesdale Nominees HGB0125                            310042001 a/c         741
Clydesdale Nominees HGB0125                            310092601 a/c       1,723
Clydesdale Nominees HGB0125                            310128001 a/c         857
Clydesdale Nominees HGB0125                            310186801 a/c         542
Clydesdale Nominees HGB0125                            310205801 a/c         446
Clydesdale Nominees HGB0125                            310231701 a/c         505
Clydesdale Nominees HGB0125                            310246501 a/c       6,825
Clydesdale Nominees HGB0125                            310254601 a/c       1,013
Clydesdale Nominees HGB0125                            310255401 a/c       5,940
Clydesdale Nominees HGB0125                            310266001 a/c         362
Clydesdale Nominees HGB0125                            310311901 a/c         660
Clydesdale Nominees HGB0125                            310589801 a/c         323
Clydesdale Nominees HGB0125                            310590101 a/c         331
Clydesdale Nominees HGB0125                            310594401 a/c         565
Clydesdale Nominees HGB0125                            700009301 a/c         729
Clydesdale Nominees HGB0125                            700066201 a/c         578
Clydesdale Nominees HGB0125                            700083201 a/c         432
Clydesdale Nominees HGB0125                            700106501 a/c         583
Clydesdale Nominees HGB0125                            59579802 a/c        1,013
Clydesdale Nominees HGB0125                            70160102 a/c        1,175
Clydesdale Nominees HGB0125                            70383302 a/c        2,719
Clydesdale Nominees HGB0125                            87093402 a/c        1,176
Clydesdale Nominees HGB0125                            310594402 a/c         165
Clydesdale Nominees HGB0125                            700207002 a/c       2,237
Clydesdale Nominees HGB0125                            70309403 a/c          534
Clydesdale Nominees HGB0125                            87093403 a/c          434
Durlacher Nominees Limited                                                37,378
Gerrard Nominees Limited 602394 a/c                                          860
Gerrard Nominees Limited 602698 a/c                                          475
Gerrard Nominees Limited 603856 a/c                                        3,040
Gerrard Nominees Limited 631118 a/c                                        4,000
Gerrard Nominees Limited 643975 a/c                                        1,800
Gerrard Nominees Limited 659442 a/c                                          650
Gerrard Nominees Limited 659792 a/c                                          640
Gerrard Nominees Limited 660137 a/c                                          500
Gerrard Nominees Limited 660302 a/c                                        1,500
Gerrard Nominees Limited 660318 a/c                                       14,500
Gerrard Nominees Limited 660430 a/c                                          230
Gerrard Nominees Limited 660632 a/c                                        1,000
Gerrard Nominees Limited 660758 a/c                                        6,000
Gerrard Nominees Limited 660851 a/c                                        6,500
Gerrard Nominees Limited 660968 a/c                                          713
Gerrard Nominees Limited 768557 a/c                                        3,350
Gerrard Nominees Limited 770101 a/c                                        2,500
Gerrard Nominees Limited 781271 a/c                                        3,000
Grieg Middleton Nominees Limited                                         276,812
Grieg Middleton Nominees Limited 126066DA a/c                                400
Grieg Middleton Nominees Limited 523475DN a/c                             50,000
Investors Bank and Trust Co.                                           5,573,225
JP Morgan (BGI Custody) 16331 a/c                                        141,498
JP Morgan (BGI Custody) 16338 a/c                                         32,914
JP Morgan (BGI Custody) 16341 a/c                                        310,734
JP Morgan (BGI Custody) 16342 a/c                                         74,836
JP Morgan (BGI Custody) 16400 a/c                                      4,277,008
JP Morgan (BGI Custody) 17011 a/c                                          9,834
JP Morgan (BGI Custody) 18408 a/c                                         44,286
JPMorgan Chase Bank                                                      750,153
Mellon Trust - US Custodian/                                              20,274
Mitsui Asset                                                               9,722
R C Greig Nominees Ltd                                                 1,854,589
R C Greig Nominees Ltd GP1 a/c                                           177,753
R C Greig Nominees Ltd SA1 a/c                                           107,326
R C Greig Nominees Ltd AK1 a/c                                           579,324
R C Greig Nominees Ltd BL1 a/c                                           135,980
R C Greig Nominees Ltd CM1 a/c                                            69,565
Reflex Nominees Ltd                                                          157
State Street Boston                                                      267,069
Trust & Custody Services Bank                                              8,221
Zeban Nominees Ltd                                                       324,203


5.      Number of shares / amount of stock acquired: NOT DISCLOSED

6.      Percentage of issued class*: N/A

7.      Number of shares / amount of stock disposed: NOT DISCLOSED

8.      Percentage of issued class*: N/A

9.      Class of security: ORDINARY SHARES OF 25p

10.     Date of transaction: NOT DISCLOSED

11.     Date listed company informed: 4 DECEMBER 2006

12.     Total holding following this notification:  23,957,272 SHARES 
        (AT 29 NOVEMBER 2006)

13.     Total percentage holding of issued class following this notification*:
        4.207%

14.     Any additional information

15.     Name of contact and telephone number for queries: 
        GUY NORRIS - 020 8457 8326

16.     Name and signature of authorised company official responsible for making
        this notification: GUY NORRIS

17.     Date of notification: 4 DECEMBER 2006

* any treasury shares held by the listed company should not be taken into
account when calculating percentage




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