Directorate Change

Stem Cell Sciences plc 19 November 2007 Press Release STEM CELL SCIENCES APPOINTS ALASTAIR RIDDELL AS CEO FOUNDER PETER MOUNTFORD ASSUMES CTO ROLE 19th November 2007 Stem Cell Sciences plc (SCS, AIM:STEM, ASX: STC), the global biotechnology company focused on the commercialisation of stem cells and stem cell technologies in research and cell-based therapies, announces today the appointment of Dr Alastair James Riddell, aged 58, as Chief Executive Officer (CEO). Dr Riddell brings to SCS extensive experience in the biotech industry, with more than 10 years experience at Board level in building companies, raising financing and negotiating deals for both public and private companies. He replaces the Company's founder, Dr Peter Mountford, who has taken the role of Chief Technology Officer as well as retaining his Executive Directorship. Most recently, Dr Riddell was Non-Executive Chairman of Surface Therapeutics until overseeing the company's acquisition by Serentis in September 2007. As CEO of Paradigm Therapeutics, Dr Riddell, with his senior team, completed major corporate licensing agreements with Johnson & Johnson and Takeda, as well as leading the negotiations for Takeda's acquisition of the company in March 2007. From 1998 to 2005, Dr Riddell was CEO of Pharmagene taking the company through several rounds of VC financing and an eventual IPO on the LSE. Previous to Pharmagene, Dr Riddell held senior management positions at Caremark, Amersham International, Centocor, Celltech, Xoma Europe and Lederle. Dr Riddell started his medical career in the Royal Army Medical Corps and the Royal Berkshire Hospital. "SCS is in a pivotal stage of its corporate development and has made great progress in developing and commercialising its innovative stem cell technologies. As a demonstrated successful leader, with extensive expertise in driving the growth of biotech companies, the Board believes that Dr Riddell is the appropriate person to lead the company to the next stage in its development," noted David Dodd, Non-Executive Chairman of SCS. "We would also like to recognise Dr Mountford, whose vision and determination has helped grow SCS to the global stem cell player it is today. In his new role, we look forward to capitalising on his recognised knowledge of the sector to fuel the future SCS product pipeline." In his role as Chief Technology Officer based in Melbourne, Australia, Dr Mountford will capitalise on his experience and expertise for sourcing and licensing innovative stem cell technologies. This will involve leveraging new business opportunities from the technology platform and expanding the company's network of academic collaborators. Commenting on his new role, Dr. Riddell stated, "Stem Cell Sciences has an excellent record in establishing valuable intellectual property in this exciting field and my task is to translate that position into commercial success in the near term and therapeutic success in the long term. The company has made a promising start in the drug discovery applications of its technology with its initial deals. I look forward to working with the company in building on these early successes and creating significant shareholder value in the future." - Ends - For further information, please contact: Stem Cell Sciences plc (United Kingdom) +44 131 662 9829 Alastair Riddell, CEO Halsin Partners (United Kingdom) +44 20 7084 5955 Mike Sinclair Talk Biotech (Australia) +61 4 2220 6036 Fay Weston Stem Cell Sciences llc (USA) +1 678 641 4029 David Dodd, Chairman of SCS plc Notes to Editors Stem Cell Sciences plc (SCS, AIM: STEM, ASX: STC) is a global biotechnology company providing the biological infrastructure of cells and cell culture media to the burgeoning stem cell research market. Stem Cell Sciences' core objective is to develop safe and effective cell-based therapies for currently incurable diseases. SCS retains all rights to its technology for therapeutic use and is targeting cell-based therapies for neurodegenerative disease and injury. Revenues from Stem Cell Sciences' research business are delivered via an integrated network of business teams and regional offices in Edinburgh and Cambridge (UK), Melbourne (Australia) and San Francisco (USA). This global reach provides the Company with the direct access to markets through experienced personnel and local business networks needed to drive SCS's business growth in each region. The key challenge for the successful application of stem cells in both research and clinical applications is the reproducible supply of pure, fully characterized stem cells and stem cell-derived specialised cells such as nerves and muscle. This represents a significant technological challenge that will require access to multiple technologies and a globally integrated stem cell initiative. To access cutting edge technologies on a rapid and on-going basis, Stem Cell Sciences has built an exceptional network of highly interactive collaborations with academic centres of excellence in the stem cell field. These collaborations have been the source of our founding technologies and continue to provide an expanding pipeline of products and intellectual property that are central to the Company's strategy and success. To facilitate research and technology transfer with its major collaborating academic institutions, Stem Cell Sciences' business and scientific teams are usually co-located on site or adjacent to the centre of excellence in independent company facilities. The Company's key collaborating institutes include the Wellcome Trust Centre for Stem Cell Research (University of Cambridge), the Institute of Stem Cell Research (University of Edinburgh), RIKEN Centre for Developmental Biology (Kobe) and the Australian Stem Cell Centre (Melbourne). Academic and commercial use of stem cells in basic research and drug discovery provides the Company with immediate and growing revenue streams and offsets the cost of technology development for full scale cell production of SCS cell-based therapeutics. For further information on the company please visit: www.stemcellsciences.com This information is provided by RNS The company news service from the London Stock Exchange

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