Opening of Share Offer on ASX

Stem Cell Sciences plc 20 March 2007 20 March 2007 Stem Cell Sciences plc ("Stem Cell Sciences", "SCS" or "the Company") Opening of Share Offer on Australian Stock Exchange Further to the announcement on 14 March 2007, Stem Cell Sciences plc, the global biotechnology company focused on the commercialisation of stem cells and stem cell technologies in research and cell-based therapies, confirms that its share offer has today opened in Australia. It is anticipated that the Company's shares will list on the Australian Stock Exchange in April 2007. A further announcement will be made when the offer closes. - Ends - For further information, please contact: Stem Cell Sciences plc 0131 662 9829 Peter Mountford, President and CEO Hugh Ilyine, Chief Operations Officer Sue Furber, Director of Finance Weber Shandwick Financial 020 7067 0700 Louise Robson or James White Notes to Editors Stem Cell Sciences plc (AIM: STEM) is a global biotechnology company, established in Melbourne, Australia in 1994, providing products in the burgeoning stem cell research and drug discovery markets, in addition to the targeted development of cell-based therapies for neurodegenerative disease and injury. The Company has established a leading intellectual property (IP) and technology portfolio that enables the commercial application of stem cells in drug discovery, providing the Company with early-stage revenue streams and technology development for at scale cell production of SCS cell-based therapeutics. SCS principal focus is in neurological disease. Revenues in the neurotech market, including pharmaceuticals, devices and diagnostics, grew 10% in 2005 to US$110 billion (Neurotech Insights, Volume 2/3 April 30 2006). SCS operates as a group of independent operations with offices and laboratories in Edinburgh and Cambridge, UK, Kobe, Japan, Melbourne, Australia and San Francisco, USA (office only). Each SCS facility is affiliated with an academic centre of excellence. These include the Institute of Stem Cell Research (ISCR), Edinburgh, UK, RIKEN Centre for Development Biology, Kobe, Japan and the Australian Stem Cell Centre, Melbourne, Australia. SCS has four business units, each dedicated to different aspects of the stem cell business opportunity. SC Proven(R) provides cell culture media (liquid formulations) and reagents that enable the growth and differentiation of stem cells. The first SC Proven(R) product, "ESGRO CompleteTM", a cell culture medium capable of consistent growth of mouse embryonic stem cells without serum or feeder cell support was launched in February 2006. This was followed by "HEScGROTM", the first animal-component free cell culture medium to enable improved growth of human embryonic stem cells, in January 2007. These products are manufactured and distributed by Chemicon International, now part of Millipore Corporation. SC Licensing licenses SCS proprietary technologies, such as Internal Ribosome Entry Site (IRES), Stem Cell Selection, hMADS (human adipose derived stem cells) and Neural Stem Cell Technology for application in laboratory-based research and discovery. SCS has licensed technology to major pharmaceutical and biotechnology companies including Merck & Co, Pfizer, Sanofi Aventis, GSK, Deltagen Inc and Lexicon Genetics Inc and others. SC Services provides specialised stem cell production for basic research and drug discovery, including high-throughput applications through an automated cell production facility in Cambridge UK. The services offered include the creation of specific cell lines for a customer, the modification of existing cell lines so that they can be grown in serum free SC Proven(R) media, and the supply of cells for drug screening in multi-well plate format. SC Therapies' goal is to develop safe and effective cell-based therapies for currently incurable diseases. Initial research is being directed to developing and characterising cell lines of potential therapeutic value in the treatment of spinal injury, Parkinson's disease, eye disease, epilepsy and Duchenne Muscular Dystrophy (DMD). Programmes to test SCS' proprietary stem cells in animal models of spinal cord injury have been initiated in a number of disease models and preclinical studies for the treatment of Duchenne Muscular Dystrophy are anticipated in 2007-8. For further information on the company please visit: www.stemcellsciences.com This information is provided by RNS The company news service from the London Stock Exchange

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