Holding(s) in Company

Synchronica PLC
09 October 2006

9 October 2006


                                Synchronica plc

                               Holding in Company



NOTIFICATIONS UNDER SECTIONS 198 TO 202 - - U.K. COMPANIES ACT



1.   Company in which shares are held:     Synchronica plc



2.   Notifiable Interest:           Ordinary Shares of 1p each



A.  FMR Corp.

    82 Devonshire Street

    Boston, MA 02109



Parent holding company of Fidelity Management & Research Company (FMRCO),
investment manager for US mutual funds, and Fidelity Management Trust Company
(FMTC), a US state chartered bank which acts as a trustee or investment manager
of various pension and trust accounts.



B.  Fidelity International Limited (FIL)

           P.O. Box HM 670

           Hamilton HMCX, Bermuda



Parent holding company for various direct and indirect subsidiaries,
including Fidelity Investment Services Ltd (FISL), Fidelity Gestion (FIGEST),
Fidelity Investments Advisory (Korea) Limited (FIA(K)L), Fidelity Investments
Management (Hong Kong) Limited (FIMHK), Fidelity Pension Management (FPM),
Fidelity Investments Japan (FIJ) and Fidelity Investments International (FII),
investment managers for various non-US investment companies and institutional
clients. (See Schedule A for listing of Registered Shareholders and their
holdings.)



3.       The notifiable interests also comprise the notifiable interest of:



           Mr. Edward C. Johnson 3d

           82 Devonshire Street

           Boston, MA 02109



           A principal shareholder of FMR Corp. and Fidelity International
Limited.



4.         The notifiable interests include interest held on behalf of
authorised unit trust schemes in the U.K., notwithstanding the exemption from
reporting pursuant to Section 209 (1)(h) of the Companies Act 1985.



5.         These notifications of disclosable interests constitute separate
notifications of interest in the shares and are combined solely for the purposes
of clarity and efficiency. Nothing herein should be taken to indicate that
Fidelity International Limited and its direct and indirect subsidiaries or Mr.
Edward C. Johnson 3d act as a group or in concert in respect of the disclosed
interests, or that they are required to submit these notifications on a joint
basis.



6.         The disclosable interests arise under section 208 (4)(b) of the Act,
namely where a person, not being the registered holder, is entitled to exercise
a right conferred by the holding of the shares or to control the exercise of
such rights, or under section 203 of the Act respectively.





Schedule A



Security: Synchronica plc




Shares Held       Management Company                Nominee/Registered Name

        1,706,000                FIL                JP Morgan, Bournemouth
           22,600                FIL                Brown Brothers Harriman Ltd A/c LUX



Total Ordinary Shares: 1,728,600



Current ownership percentage: 4.75%



Date Company notified: 6 October 2006


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