Directorate Change

Synexus Clinical Research PLC
18 September 2006


Synexus Clinical Research plc appoints
Paul McCluskey as Chief Financial Officer

Synexus Clinical Research plc ("Synexus") the international organisation
providing patient recruitment to the global clinical trials industry, is pleased
to announce the appointment of Paul McCluskey as Chief Financial Officer with
immediate effect.

Most recently, Paul, aged 42, was the European Managing Director of the formerly
autonomous subsidiary of RHM plc, RHM Ingredients Ltd, which was acquired by
private American owners. He is a fellow of the Institute of Chartered
Accountants and previously held finance positions with BAE Systems plc and
GlaxoSmithKline plc. Paul succeeds Chris Neilson, the previous Finance Director
of Synexus, who is leaving the company to pursue other opportunities. The board
would like to thank Chris and wish him well for the future.

Michael Fort, CEO of Synexus, commented

"We are delighted to have attracted Paul to Synexus. He has considerable
experience of managing acquisitions and integrating those operations into a
unified business. Synexus' strategy is to build, through targeted acquisitions,
an international patient recruitment capability to manage large numbers of
clinical trial patients for pharmaceutical clients. Paul's experience in
integrating businesses, systems and management teams will strengthen our overall
capabilities as we continue to expand."


The following information is given in respect of Paul McCluskey as required by
Schedule 2 paragraph (g) of the AIM Rules.

Directorships held within the previous five years

Newly Weds Foods (Europe) Limited

Newly Weds Foods Limited

NWF Europe Limited

RHM Ingredients Limted

Press enquiries:
Synexus Clinical Research plc                    Tel: [phone]
Michael Fort, Chief Executive
Biddicks - Financial Public Relations            Tel: [phone]
Zoe Biddick




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