Holding(s) in Company

Synexus Clinical Research PLC
21 April 2006


SYNEXUS CLINICAL RESEARCH PLC (the "Company")

NOTIFICATION OF MAJOR INTERESTS IN SHARES

The Company received notification on 19 April 2006 that, as of 13 April 2006,
Murray VCT 4 PLC no longer has a notifiable interest in the Company. The
notification was issued by Aberdeen Asset Management PLC.






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