Holding(s) in Company

Synexus Clinical Research PLC
29 March 2006


SYNEXUS CLINICAL RESEARCH PLC

29 MARCH 2006

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

SYNEXUS CLINICAL RESEARCH PLC

2. Name of shareholder having a major interest

MURRAY VCT 4 PLC

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

AS IN 2

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

SEE ADDITIONAL INFORMATION BELOW

5. Number of shares / amount of stock acquired

N/A

6. Percentage of issued class

N/A

7. Number of shares / amount of stock disposed

300,000

8. Percentage of issued class

1.32%

9. Class of security

ORDINARY GBP0.10 SHARES

10. Date of transaction

24 MARCH 2006

11. Date company informed

28 MARCH 2006

12. Total holding following this notification

882,794

13. Total percentage holding of issued class following this notification

3.87%

14. Any additional information

FIGURES BASED ON SHARES IN ISSUE OF 22,791,196.

NOTIFICATION ISSUED BY ABERDEEN ASSET MANAGEMENT PLC.

15. Name of contact and telephone number for queries

16. Name and signature of authorised company official responsible for making
this notification

Date of notification

29 MARCH 2006








                      This information is provided by RNS
            The company news service from the London Stock Exchange