Director Shareholding

microgen

Information Management Solutions

www.microgen.co.uk

23 September 2005

Notification of Directors' Interests

Microgen plc announces that on 22 September 2005 awards of options over
Ordinary Shares of 5p each were made to the following Directors under the
Microgen 1999 Executive Share Option Scheme:

Director:                             Michael Scott Phillips                   
                                                                               
Number of Shares:                     100,000                                  
                                                                               
Exercise price in pence:              70.5p                                    
                                                                               
Date of Grant:                        22 September 2005                        
                                                                               
Period of Exercise:                   22 September 2008 to 22 September 2015   
                                                                               
Total Number of Shares over which     612,145                                  
Options held following this                                                    
notification:                                                                  



Director:                             David John Sherriff                      
                                                                               
Number of Shares:                     100,000                                  
                                                                               
Exercise price in pence:              70.5p                                    
                                                                               
Date of Grant:                        22 September 2005                        
                                                                               
Period of Exercise:                   22 September 2008 to 22 September 2015   
                                                                               
Total Number of Shares over which     450,000                                  
Options held following this                                                    
notification:                                                                  

If you require further information please contact:

G.E. Liddle, Company Secretary 01252 772 313