Collaboration Agreement

Avacta Group plc Collaboration Agreement with UCB and sponsorship from the DTI Avacta Group plc ("Avacta" or the "Company"), which develops detection and analysis technology aimed at the defence & security, pharmaceutical and clinical diagnostics markets, announces an agreement with UCB's Celltech Antibody Centre of Excellence ("UCB") together with the commencement of a Department of Trade and Industry ("DTI") sponsored Collaborative Research and Development project. Avacta will be the lead partner, working with UCB, in developing analytical technology to measure the biophysical properties of therapeutic antibodies and develop algorithms that use these data to predict properties that are critical to later stage performance. Avacta believes that strong demand exists in the biopharmaceutical industry for techniques to analyse very small quantities of biological therapeutic materials at an early stage of the development process. The analytical techniques it is developing with UCB are aimed at enabling companies to measure or predict certain key properties of experimental compounds at an early stage in the development pipeline, prior to committing further investment. The goal is to predict as early as possible whether problems related to properties such as aggregation, stability and viscosity will occur in later stages of development, manufacturing or delivery. UCB will own the intellectual property rights generated relating specifically to its therapeutic molecules, whilst Avacta will own the rights to the new analytical technology and predictive tools. Avacta plans to monetise the results of this project through one or more routes including potentially the supply of innovative instrumentation, licensing of the developed technologies and the provision of high value contract screening services via Avacta's analytical services subsidiary. Prof. Alastair Smith, Chief Executive, Avacta, commented: "There are difficulties faced by biopharmaceutical companies in predicting therapeuticprotein performance at an early stage, thereby leading to increased risk of eventual product failure. This project addresses these issues by developing innovative biophysical tools for the rapid analysis of small volumes of compounds and predictive tools which may reduce the attrition rate of candidates in the development pipeline, thereby saving these companies many millions. "We know that considerable demand exists for analytical techniques and tools capable of predicting at an early stage the viability of molecules as clinical products and are very fortunate to have joined forces with UCB and to have obtained sponsorship from the DTI." Dr. Richard Pither, Vice President Research - Biologicals, UCB Celltech (Antibody Centre of Excellence), added: "The team at Avacta represents the cutting edge of biophysics research combined with a commercial focus. This project is important to UCB in that success may help us to select and develop better products, more quickly. We look forward to working with Avacta." 24 August 2006 Enquiries: Avacta Group plc Tel: 0870 835 4367 Alastair Smith, Chief Executive Nexus Financial Ltd Tel: 020 7451 7050 Nicholas Nelson, Director nicholas.nelson@nexusgroup.co.uk Kathy Boate Notes to Editors: About Avacta Avacta was spun-out from the University of Leeds in January 2004 by its current management team as a biophysics company, with the aim of combining the disciplines of physics and biology to develop innovative technologies to address needs in the homeland security, pharmaceutical and clinical diagnostics markets. The goal of Avacta is to integrate the best elements of each discipline into technologies suitable to address specific identified needs in the targeted markets. In seeking to achieve this goal Avacta intends to combine its in-house expertise in laser spectroscopy, nanotechnology and instrumentation engineering with its understanding of the versatility and specificity of biology. Avacta has two core activities: * the development of detection technology platforms designed to meet the needs of its target markets * the provision of analytical services relating to the chemical and physical analysis of materials to a range of companies, principally in the pharmaceutical, healthcare and personal care sectors. Avacta was admitted to trading on AIM on 8 August 2006. About UCB UCB (www.ucb-group.com) is a leading global biopharmaceutical company dedicated to the research, development and commercialisation of innovative pharmaceutical and biotechnology products in the fields of central nervous system disorders, allergy/respiratory diseases, immune and inflammatory disorders and oncology. UCB focuses on securing a leading position in severe disease categories. Employing over 8,300 people in over 40 countries, UCB achieved revenue of 2.3 billion euro in 2005. UCB is listed on the Euronext Brussels Exchange and its worldwide headquarters are located in Brussels, Belgium.
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