Annual Information Update

Immediate Release: Wednesday 20th May 2009 CLS Holdings plc (the "Company" or "CLS") Annual Information Update ("AIU") In accordance with Prospectus Rule 5.2, the following information has been published or made available to the public in the 12 months preceding this announcement in compliance with laws and rules dealing with the regulation of securities, issues of securities and securities markets. In accordance with Prospectus Rule 5.2.7 it is acknowledged that, although the information contained in each of the documents listed below was accurate and up to date when originally published, such information may at any time become out of date due to changing circumstances. This AIU can be found in the Press Centre - Regulatory News section of our website at www.clsholdings.com. The following UK regulatory announcements have been made via a Regulatory Information Service. A full copy of these announcements can be viewed on the Company's price page of the London Stock Exchange website at www.londonstockexchange.com. The code for CLS, which may be required for search purposes, is CLI. Copies of these announcements may also be found via CLS' website in the Press Centre - Regulatory News section. Date of Brief description of announcement Announcement 19 May 09 Result of AGM 15 May 09 Interim Management Statement 01 May 09 Director/PDMR Shareholding 01 May 09 Notification of Major Interest in Shares 24 Apr 09 Annual Financial Report 09 Apr 09 Holding(s) in Company 31 Mar 09 Director/PDMR Shareholding 25 Mar 09 Final Results - Part 1 25 Mar 09 Final Results - Part 2 25 Mar 09 Final Results - Part 3 26 Jan 09 Director/PDMR Shareholding 22 Jan 09 Director/PDMR Shareholding 22 Jan 09 Holding(s) in Company 12 Jan 09 Director/PDMR Shareholding 08 Jan 09 Completion of Tender Offer 23 Dec 08 Result of Tender offer 18 Dec 08 Result of EGM and Tender Offer 16 Dec 08 Sale of Property 09 Dec 08 Director/PDMR Shareholding 02 Dec 08 Full Occupancy at Cambridge House 01 Dec 08 Special Tender Offer 27 Nov 08 Board Change 27 Nov 08 Special Tender Offer 26 Nov 08 Correction: Director/PDMR Shareholding 24 Nov 08 Director/PDMR Shareholding 19 Nov 08 Transaction in Own Shares 19 Nov 08 Director/PDMR Shareholding 18 Nov 08 Interim Management Statement 14 Nov 08 Holding in Bulgarian Land Development plc 14 Nov 08 Result of EGM and Tender Offer 12 Nov 08 New Letting Agreement 04 Nov 08 Director/PDMR Shareholding 27 Oct 08 Director/PDMR Shareholding 20 Oct 08 Tender Offer 16 Oct 08 Total Voting Rights 13 Oct 08 Director/PDMR Shareholding 13 Oct 08 Transaction in Own Shares 13 Oct 08 Transaction in Own Shares 08 Oct 08 Transaction in Own Shares 07 Oct 08 Transaction in Own Shares 01 Oct 08 Transaction in Own Shares 01 Oct 08 Transaction in Own Shares 30 Sep 08 REG-CLS Holdings PLC: Transaction in Own Shares 09 Sep 08 Announcement of New Letting 09 Sep 08 Announcement of New Letting 01 Sep 08 Transaction in Own Shares 29 Aug 08 Half-yearly Report - Part 2 29 Aug 08 Half-yearly Report - Part 1 28 Aug 08 Sale of Properties 28 Aug 08 Sale of Properties 22 Aug 08 Transaction in Own Shares 21 Aug 08 New Letting Agreement 20 Aug 08 Transaction in Own Shares 19 Aug 08 Transaction in Own Shares 18 Aug 08 Transaction in Own Shares 18 Aug 08 Sale of Properties 15 Aug 08 Transaction in Own Shares 11 Aug 08 Transaction in Own Shares 06 Aug 08 Transaction in Own Shares 30 Jul 08 Transaction in Own Shares 29 Jul 08 Transaction in Own Shares 28 Jul 08 Transaction in Own Shares 28 Jul 08 Transaction in Own Shares 24 Jul 08 Transaction in Own Shares 23 Jul 08 Transaction in Own Shares 22 Jul 08 Transaction in Own Shares 21 Jul 08 Transaction in Own Shares 18 Jul 08 Transaction in Own Shares 17 Jul 08 Transaction in Own Shares 16 Jul 08 Transaction in Own Shares 16 Jul 08 Holding(s) in Company 15 Jul 08 Transaction in Own Shares 09 Jul 08 Transaction in Own Shares 08 Jul 08 Transaction in Own Shares 07 Jul 08 Transaction in Own Shares 04 Jul 08 Transaction in Own Shares 03 Jul 08 Transaction in Own Shares 02 Jul 08 Transaction in Own Shares 01 Jul 08 Transaction in Own Shares 30 Jun 08 Close Period Share Purchase 30 Jun 08 Director/PDMR Shareholding 27 Jun 08 Transaction in Own Shares 27 Jun 08 Sale of Properties 25 Jun 08 Transaction in Own Shares 24 Jun 08 Transaction in Own Shares 23 Jun 08 Transaction in Own Shares 17 Jun 08 Holding(s) in Company 13 Jun 08 Transaction in Own Shares 12 Jun 08 Transaction in Own Shares 11 Jun 08 Transaction in Own Shares 10 Jun 08 Transaction in Own Shares 10 Jun 08 Transaction in Own Shares 06 Jun 08 Transaction in Own Shares 05 Jun 08 Transaction in Own Shares 05 Jun 08 Transaction in Own Shares 04 Jun 08 Transaction in Own Shares 31 May 08 Transaction in Own Shares 27 May 08 Transaction in Own Shares 22 May 08 Transaction in Own Shares 22 May 08 Director/PDMR Shareholding 22 May 08 Transaction in Own Shares 21 May 08 Transaction in Own Shares 20 May 08 Transaction in Own Shares 20 May 08 Result of AGM 19 May 08 Transaction in Own Shares 19 May 08 Sale of Properties 15 May 08 Transaction in Own Shares 15 May 08 Interim Management Statement 14 May 08 Transaction in Own Shares 14 May 2008 Annual Information Update The Company has submitted filings to Companies House, in relation to the allotment of shares, appointment and resignations of directors, amendments to the Memorandum and Articles of Association and the purchase of its own shares which were either cancelled or held as treasury shares. Copies of these documents can be found on the Companies House website at www.companieshouse.gov.uk or through Companies House Direct at www.direct.companieshouse.gov.uk. The Company's Annual Report for the period ending 31 December 2008 (which was filed with the UKLA Document Viewing Facility on 24 April 2009) can be found on the Company's website, as can the Interim Report 2008 published on 29 August 2008, the 2009 AGM documentation and the results of the proxy votes. The resolutions passed at the AGM under special business were filed with the UKLA Document Viewing Facility on 19 May 2009. Further information regarding the Company and its activities is available at www.clsholdings.com A copy of this Annual Information Update and all documents referred to in it can be obtained from the Company's registered office: CLS Holdings plc 86 Bondway London SW8 1SF For further information contact: David Fuller Deputy Company Secretary CLS Holdings plc Tel: 020 7582 7766

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CLS Holdings (CLI)
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