Holding(s) in Company

The Company has been notified today that GAM London Limited has a notifiable
interest in 3,777,227 Ordinary Shares of 5p each which, represents 7.881% of
the issued share capital of Oxford Instruments plc.

The shares to which this notification relates are registered as follows:

Holding    Owned By                     Advised By            %          
                                                                         
800,000    GAM Sterling Managed Fund    GAM London Limited    1.669      
                                                                         
119,000    GAM US Dollar Managed Fund   GAM London Limited    0.248      
                                                                         
649,000    GAM International Growth     GAM London Limited    1.354      
           Fund                                                          
                                                                         
486,000    GAM UK Diversified           GAM London Limited    1.014      
                                                                         
77,000     GAM Exempt Trust - U.K.      GAM London Limited    0.161      
           Opportunities                                                 
                                                                         
759,000    SJP/GAM Managed - Life       GAM London Limited    1.584      
                                                                         
459,227    JRA/GAM Managed - Pension    GAM London Limited    0.958      
                                                                         
428,000    St James's Place Recovery    GAM London Limited    0.893      
           Unit Trust                                                    
                                                                         
3,777,227                                                     7.881      

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