Holding(s) in Company

Advanced Medical Solutions Grp PLC
23 April 2007


TR-1:    NOTIFICATION OF MAJOR INTERESTS IN SHARES 

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached

2. Reason for the notification     (please tick the appropriate box or boxes)
An acquisition or disposal of voting rights                                               X
An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached
An event changing the breakdown of voting rights
Other (please specify): Initial notification of shareholding under Transparency
Directive

3. Full name of person(s) subject to the             INVESCO English & International Trust
notification obligation:

4. Full name of shareholder(s) (if different
from 3.):

5. Date of the transaction (and date on which                      16/04/07
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                                  17/04/07

7. Threshold(s) that is/are crossed or reached:                     5%, 4%

8. Notified details:

A: Voting rights attached to shares
Class/type of     Situation previous to the   Resulting situation after the triggering transaction
shares            Triggering transaction      (i)

 if possible      Number of     Number of     Number of    Number of voting      % of voting rights
using the ISIN    Shares        Voting Rights shares       rights
CODE
                                                           Direct   Indirect     Direct    Indirect

Ordinary Shares   7,812,159     7,812,159     7,000,000             7,000,000              4.92%
5p (GB0004536594)


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)
Number of voting rights                             % of voting rights

7,000,000                                           4.92%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:

Chase Nominees - 7,000,000


Proxy Voting:
10. Name of the proxy holder:                                  na

11. Number of voting rights proxy holder will cease to hold:   na

12. Date on which proxy holder will cease to hold voting       na
rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               [phone]




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