Holding(s) in Company

Allergy Therapeutics PLC
11 May 2005


Schedule 10

NOTIFICATION OF MAJOR INTERSTS IN SHARES

1.                  Name of Company

Allergy Therapeutics plc

2.                  Name of shareholder having a major interest

Fidelity International Limited

3.                  Please state whether notification indicates that it is in
respect of holding of the shareholder names in 2 above or in respect of a
non-beneficial interest or in the case of children under the age of 18

Non-beneficial interest

4.                  Name of the registered holder(s) and, if more than one
holder, the number of share held by each of them

Nominee/registered name           Share held           Management Company
JP Morgan, Bournemouth             1,572,100           Fidelity Inv Services Ltd
Bank of New York, Brussels           359,662           Fidelity Pension Mgmnt(FPM)
Bankers Trust London                 135,700           FPM
CITIBANK London                      128,400           FPM
Clydesdale Bank plc                   71,900           FPM
JP Morgan, Bournemouth               288,500           FPM
Mellon Bank                          325,400           FPM
Midland Securities Services           74,300           FPM
Northern Trust London                618,500           FPM
State STR BK and TR Co London        227,084           FPM
Brown Bros Harrimn Ltd LUX           650,000           FPM
Bank of New York, Brussels            81,900           FIL

5.                  Number of shares/amount of stock acquired

650,000

6.                  Percentage of issued class

1.03%

7. Number of shares/amount of stock disposed

-

8. Percentage of issued class

-

9. Class of security

Ordinary shares

10. Date of transaction

Not notified

11. Date company informed

10th May 2005

12. Total holding following this notification

4,533,446

13.              Total percentage holding of issued class following this
notification

7.20%

14. Any additional items

Notifiable interest also comprises of Mr.Edward C. Johnson 3d A principal
Shareholder of Fidelity International Limited

15. Name of contact and telephone number for queries

Ian Postlethwaite - 01903 844721

16.              Name and signature of authorised company official responsible
for make this notification

Ian Postlethwaite

Date of notification

10th May 2005

The FSA does not give any express or implied warranty as to the accuracy of this
document or material and does not accept liability for error or omission. The
FSA is not liable for any damages (including, without limitation, damages for
loss of business or loss of profits) arising in contract, tort or otherwise from
the use of or inability to use this document, or any material contained in it,
or from any action or decision taken as a result of using this document or any
such material.






                      This information is provided by RNS
            The company news service from the London Stock Exchange