Holding(s) in Company

Allergy Therapeutics PLC
05 March 2007





TR-1:               notification of major interests in shares



1. Identity of the issuer or the underlying issuer of existing         Allergy Therapeutics plc
shares to which voting rights are attached:


2. Reason for the notification (please tick the appropriate box or boxes):


An acquisition or disposal of voting rights                  X


An acquisition or disposal of financial instruments which may result in the acquisition of
shares already issued to which voting rights are attached


An event changing the breakdown of voting rights



3. Full name of person(s) subject to the notification           Fidelity International Limited (FIL)
obligation:


4. Full name of shareholder(s) (if different from 3.):          See 8 below


5. Date of the transaction and date on which the threshold is   27 February 2007
crossed or reached:


6. Date on which issuer notified:                               1 March 2007

                                             
7. Notified details:




A: Voting rights attached to shares

Class/type of shares   Situation previous     Resulting situation after the triggering transaction
                       to the Triggering
if possible using the  transaction

ISIN CODE              Number of  Number of   Number of    Number of voting rights   % of voting rights
                       Shares     Voting      shares
                                  Rights      Direct       Direct      Indirect       Direct    Indirect

GB00B02LCQ05                11,597,973        -            -           11,093,473     -         13.54%

ORD £0.001




B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument                           Period/ Date              that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted






Total (A+B)

Number of voting rights                            % of voting rights

11,093,473                                         13.54%





8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:


Fidelity International Limited (FIL) is the parent holding company for various direct and indirect subsidiaries,
including Fidelity Fund Management Limited (FFML), Fidelity Investment Services Ltd (FISL), Fideilty Gestion (FIGEST),
Fideilty Investments Advisory (Korea) Limited (FIAKL), Fidelity Investments Management (Hong Kong) Limited (FIMHK),
Fidelity Pension Management (FPM), Fidelity Investments Japan (FIJ) and Fidelity Investments International (FII),
investment managers for various non-US investment companies and institutional clients.


UK Nominee                          Management Company                  Shares Held

State Str Bk and Tr Co LNDN         FPM                                 131,284
Northern Trust London               FPM                                 602,000
Midland Securities Services         FPM                                 174,300
Mellon Bank                         FPM                                 684,400
JP Morgan, Bournemouth              FPM                                 947,136
JP Morgan, Bournemouth              FISL                                5,724,798
JP Morgan, Bournemouth              FIL                                 1,501,512
Brown Bros Harrimn Ltd Lux          FIL                                 869,043
Bank of New York, Brussels          FPM                                 459,000

Total                                                                   11,093,473





Proxy Voting:


9. Name of the proxy holder:                                       Fidelity International Limited (FIL)


10. Number of voting rights proxy holder will cease to hold:       504,500


11. Date on which proxy holder will cease to hold voting rights:   27 February 2007


12. Additional information:                  The disclosure threshold was crossed due to a non-market
                                             transaction







                      This information is provided by RNS
            The company news service from the London Stock Exchange