Holding in Company

AstraZeneca PLC
13 June 2001



COMPANIES ACT 1985 SECTION 198
DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES

ON 12 JUNE 2001 WE WERE INFORMED THAT AS OF 11 JUNE 2001, BARCLAYS PLC,
THROUGH ITS SUBSIDIARY BARCLAYS BANK PLC, HAD A NOTIFIABLE INTEREST IN THE
USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC OF 53,131,128 SHARES WHICH
REPRESENTS 3.01 PER CENT OF THE ISSUED ORDINARY CAPITAL OF THE COMPANY. 

G H R MUSKER
COMPANY SECRETARY