Holding(s) in Company

AstraZeneca PLC 24 November 2005 Companies Act 1985 Section 198 Disclosure of Interest in Voting Shares in Public Companies On 24 November 2005 we were informed by The Capital Group Companies, Inc., a registered investment manager in the U.S., that on 22 November 2005 its interest in the USD0.25 Ordinary Shares of AstraZeneca PLC had increased to 195,493,748 shares (12.30 per cent of the current issued ordinary capital) from the previously notified level of 191,743,910 shares (12.00 per cent of the issued ordinary capital at that time). The reason for this announcement is that, within the said holding of 12.30 per cent of the issued ordinary capital of AstraZeneca PLC, Capital Research and Management Company, an affiliate of The Capital Group Companies, Inc., has increased its interest in these shares to 80,646,241 shares (5.07 per cent). G H R Musker Company Secretary 24 November 2005 This information is provided by RNS The company news service from the London Stock Exchange

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AstraZeneca (AZN)
UK 100

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