Transaction in Own Shares

AstraZeneca PLC
01 September 2006


                     REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 31 August 2006, it purchased for cancellation
525,000 ordinary shares of AstraZeneca PLC at a price of 3390 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,558,439,684.


G H R Musker
Company Secretary
1 September 2006


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