Transaction in Own Shares

AstraZeneca PLC
30 November 2006

REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the month of November, AstraZeneca PLC announced that
under the terms of that programme it purchased for cancellation 378,893 ordinary
shares of AstraZeneca PLC at a price of 2997.49 pence per share on 29 November
2006. Upon the cancellation of these shares, the number of shares in issue will
be 1,535,583,131.



G H R Musker
Company Secretary
30 November 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange