Transaction in Own Shares

AstraZeneca PLC
01 December 2006

REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the month of November, AstraZeneca PLC announced that
under the terms of that programme it purchased for cancellation 382,024 ordinary
shares of AstraZeneca PLC at a price of 2972 pence per share on 30 November
2006.


In addition, AstraZeneca PLC announced that on the same date, it purchased for
cancellation 500,000 ordinary shares of AstraZeneca PLC at a price of 2973 pence
per share.


Upon the cancellation of all of the shares purchased on that date, the number of
shares in issue will be 1,534,703,123.





G H R Musker
Company Secretary
1 December 2006


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