Transaction in Own Shares

AstraZeneca PLC
17 September 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC



AstraZeneca PLC announced that on 14 September 2007, it purchased for
cancellation 991,387 ordinary shares of AstraZeneca PLC at a price of 2373 pence
per share.



Some of these shares were purchased under the terms of the previously announced
irrevocable, non-discretionary share repurchase programme for the period 2 July
2007 to 31 October 2007.



Upon the cancellation of these shares, the number of shares in issue will be
1,477,860,904.





G H R Musker

Company Secretary

17 September 2007


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