Holding in Company

Finsbury Life Sciences Inv Tst PLC
29 October 2001


                                 SCHEDULE 10

                  NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company

Finsbury Life Sciences Investment Trust PLC

2) Name of shareholder having a major interest

HSBC Investment Bank plc

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18

As above

4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them

James Capel (Nominees) Limited                    2,475,300

James Capel (Nominees) Limited - CHTY               1,404,600

James Capel (Nominees) Limited - RA                    12,000

James Capel (Nominees) Limited - CHRAS               12,000

James Capel (Nominees) Limited - Channel Islands     163,000

Not stated                                        141,700

5) Number of shares/amount of stock acquired

not stated

6) Percentage of issued class

not stated

7) Number of shares/amount of stock disposed

not stated

8) Percentage of issued class

not stated

9) Class of security

Ordinary shares of 25p each


10) Date of transaction

24 October 2001

11) Date company informed

26 October 2001

12) Total holding following this notification
4,208,600
13) Total percentage holding of issued class following this notification

13.98%

14. Any additional information


None

15) Name of contact and telephone number for queries
David Fallon

Close Finsbury Asset Management Limited

Secretary

Tel: [phone]

29 October 2001