Blocklisting Interim Review

Cambridge Antibody Tech Group PLC
30 September 2005


                        BLOCK LISTING SIX MONTHLY RETURN


Information provided on this form must be typed or printed electronically.


To:   The FSA


Date: 30 September 2005


Name of applicant:                                         Cambridge Antibody Technology Group plc

Name of scheme:                                            Shares Awarded to Non Executive Directors

Period of return:                           From:          1 April 2005           To:        30 September 2005

Balance under scheme from previous return:                 46,910

The amount by which the block scheme has been increased,   Nil
if the scheme has been increased since the date of the
last return:

Number of securities issued/allotted under scheme during   4,027
period:

Balance under scheme not yet issued/allotted at end of     42,883
period

Number and class of securities originally listed and the   22,136,251 ordinary 10 pence shares
date of admission
                                                           25 March 1997

Total number of securities in issue at the end of the      51,639,868
period


Name of contact:                                           Justin Hoskins

Address of contact:                                        Milstein Building, Granta Park, Cambridge CB1 6GH

Telephone number of contact:                               01223 471 471



SIGNED BY   Justin Hoskins, Company Secretary

Director/company secretary/suitably experienced employee/duly authorised
officer,for and on behalf of


Cambridge Antibody Technology Group plc

Name of applicant


If you knowingly or recklessly give false or misleading information you may be
liable to prosecution.


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