Directors Shareholding(s)

Cambridge Antibody Tech Group PLC
4 December 2000



Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
James Foght

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
163

8   Percentage of issued class:
0.00046%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
163

16  Total percentage holding of issued class following this notification:
0.00046%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 262233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Aaron Klug

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
163

8   Percentage of issued class:
0.00046%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
28,220

16  Total percentage holding of issued class following this notification:
0.08%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
John Stocker

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
163

8   Percentage of issued class:
0.0046%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
3,292

16  Total percentage holding of issued class following this notification:
0.0094%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Uwe Bicker

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
163

8   Percentage of issued class:
0.00046

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
2,151

16  Total percentage holding of issued class following this notification:
0.006%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Paul Nicholson

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2 

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
163

8   Percentage of issued class:
0.00046%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
4,434

16  Total percentage holding of issued class following this notification:
0.0126%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
01763 263233

25  Name of company official responsible for making notification:
Company Secretary




Schedule 11 - Notification of interests of Directors and Connected Persons

1   Name of company:
Cambridge Antibody Technology

2   Name of director:
Peter Garland

3   Please state whether notification indicates that it is in respect of     
holding of the director named in 2 above or holding of that person's spouse or
children under the age of 18 or in respect of a non- beneficial interest:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of 
shares held by each of them (if notified):
As in 2

5   Please state whether notification relates to a person(s) connected with  
the director named in 2 above and identify the connected person(s):


6   Please state the nature of the transaction. For PEP transactions please  
indicate whether general/single co PEP and if discretionary/non discretionary:


7   Number of shares/amount of stock acquired:
327

8   Percentage of issued class:
0.00093%

9   Number of shares/amount of stock disposed:
n/a

10  Percentage of issued class:
n/a

11  Class of security:
10p ordinary shares

12  Price per share:
£30.54

13  Date of transaction:
1 December 2000

14  Date company informed:
1 December 2000

15  Total holding following this notification:
49,827

16  Total percentage holding of issued class following this notification:
0.14%

If a director has been granted options by the company, please complete the
following fields:

17  Date of grant:


18  Period during which or date on which exercisable:


19  Total amount paid (if any) for grant of the option:


20  Description of shares or debentures involved: class, number:


21  Exercise price (if fixed at time of grant) or indication that price is to
be fixed at time of exercise:


22  Total number of shares or debentures over which options held following
this notification:


23  Contact name for queries:
Diane Mellett

24  Contact telephone number:
017630263233

25  Name of company official responsible for making notification:
Company Secretary


Additional Information: