Holding in Company

Cambridge Antibody Tech Group PLC
11 October 2001


                                 SCHEDULE 10

                  NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company
Cambridge Antibody Technology


2) Name of shareholder having a major interest
Capital Group Companies Inc.


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18
Non Beneficial


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them
State Street Nominees Limited (22,200) Chase Nominees Limited (269,000)
Midland Bank plc (121,000) Nortrust Nominees (24,500) Bank of New York
Nominees (18,600) Chase Nominees Limited (114,800) Bankers Trust (190,000)
Morgan Guaranty (16,000) Nortrust Nominees (48,504) Deutsche Bank AG (12,800)
Bank One London (8,500) State Street Nominees Limited (5,400) Chase Nominees
Limited (8,700) State Street Nominees Limited (205,000)


5) Number of shares/amount of stock acquired
Not advised


6) Percentage of issued class
Not known


7) Number of shares/amount of stock disposed
Not applicable


8) Percentage of issued class
Not applicable


9) Class of security
Ordinary 10p shares


10) Date of transaction
Holding acquired through transactions of several subsidiary companies. Dates
of transactions not disclosed


11) Date company informed
10 October 2001


12) Total holding following this notification
1,065,004



13) Total percentage holding of issued class following this notification
3%


14) Any additional information



15) Name of contact and telephone number for queries
Diane Mellett 01763 263233


16) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of notification 11 October 2001