Holding(s) in Company

Cambridge Antibody Tech Group PLC
15 February 2005

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company

Cambridge Antibody Technology Group plc

2)   Name of shareholder having a major interest

Legal & General Investment Management Limited

3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18


It is not known whether the interests notified to the Company are in respect of
beneficial or non beneficial holdings.


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them


HSBC Global Custody Nominee (UK) Ltd A/c 914945  18,502

HSBC Global Custody Nominee (UK) Ltd A/c 775245  159,002

HSBC Global Custody Nominee (UK) Ltd A/c 357206  1,155,664

HSBC Global Custody Nominee (UK) Ltd A/c 747381  99,100

HSBC Global Custody Nominee (UK) Ltd A/c 866203  73,500

HSBC Global Custody Nominees (UK) Ltd A/c 916681  3,000

HSBC Global Custody Nominee (UK) Ltd A/c 360509  61,885


5)   Number of shares/amount of stock acquired

Not stated


6)   Percentage of issued class

Not stated

7)   Number of shares/amount of stock disposed

None

8)   Percentage of issued class

N/A

9)   Class of security

Ordinary 10 pence shares

10)  Date of transaction

Not stated

11)  Date company informed

14 February 2005

12)  Total holding following this notification

1,570,653 Ordinary 10 pence shares



13)  Total percentage holding of issued class following this notification

3.05%

14)  Any additional information

None


15)  Name of contact and telephone number for queries

Justin Hoskins 01223 898589

16)  Name and signature of authorised company official responsible for
     making this notification


Diane Mellett, Company Secretary



Date of notification: 15 February 2005





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