Director/PDMR Shareholding

RNS Number : 3147C

Epistem Holdings plc

15 October 2015

Epistem Holdings Plc ("Epistem" or the "Company")

Directors' Shareholdings

Epistem today provides an update regarding the Company's share investment plan, details of which were announced on 13 July 2009.

As a result of the subscription for Partnership Shares and the award of Matching Shares, executive Directors, Dr Catherine Booth, John Rylands & Dr Allan Brown and Matthew Walls each increased their beneficial interests in the Company by 951 ordinary shares of 1.5p each. These shares were acquired on 28 April 2015, 28 May 2015, 26 June 2015, 28 July 2015, 28 August 2015 and 28 September 2015 at prices of 317p, 285p, 275p, 240p, 193p and 180p respectively.

Following these transactions, the current beneficial interests of the executive Directors are set out below:

Ordinary Shares %

Dr Catherine Booth 988,126 9.35%

John Rylands 198,024 1.87%

Matthew Walls 13,771 0.13%

Dr Allan Brown 2,712 0.03%

For further details please contact:

Epistem Holdings Plc

Dr Ian Gilham: Chairman ++44 (0)161 606 7258

John Rylands: Finance Director

Peel Hunt LLP

James Steel ++44 (0)207 418 8900