Annual Information Update

GlaxoSmithKline PLC
27 March 2008

  ANNUAL INFORMATION UPDATE FOR GLAXOSMITHKLINE PLC FOR THE 12 MONTHS UP TO 27
                                   MARCH 2008




In accordance with the requirements of Prospectus Rules PR 5.2.1R please find below an Annual Information Update for 
GlaxoSmithKline plc ("The Company"). The information referred to in this update was up to date at the time the 
information was published, but some information may now be out of date.

To avoid an unnecessarily lengthy document the following are summaries of the information and documents published or 
made available to the public, by the Company throughout the twelve months ended 27 March 2008.


1.      Announcements made via RNS, a Regulatory Information Service.

The announcements listed below were published on the London Stock Exchange via RNS, a Regulatory Information Service and
can be obtained from their website www.londonstockexchange.com  or the Company's website www.gsk.com.

Date             Headline
26/03/2008       Transaction in own shares
26/03/2008       Director/PDMR Shareholding
25/03/2008       Transaction in own shares
20/03/2008       Transaction in own shares
19/03/2008       Annual Report and Accounts
19/03/2008       Transaction in Own Shares
18/03/2008       Transaction in Own Shares
17/03/2008       Transaction in Own Shares
17/03/2008       Transaction in Own Shares
14/03/2008       Transaction in Own Shares
13/03/2008       Transaction in Own Shares
12/03/2008       Transaction in Own Shares
12/03/2008       Director/PDMR Shareholding
11/03/2008       Transaction in Own Shares
10/03/2008       Transaction in Own Shares
10/03/2008       Director/PDMR Shareholding
07/03/2008       Transaction in Own Shares
07/03/2008       Transaction in Own Shares
05/03/2008       Transaction in Own Shares
04/03/2008       Transaction in Own Shares
03/03/2008       Transaction in Own Shares
03/03/2008       Total Voting Rights
29/02/2008       Transaction in Own Shares
28/02/2008       Annual Report and Accounts
28/02/2008       Transaction in Own Shares
27/02/2008       Transaction in Own Shares
26/02/2008       Director/PDMR Shareholding
26/02/2008       Transaction in Own Shares
25/02/2008       Director/PDMR Shareholding
25/02/2008       Transaction in Own Shares
22/02/2008       Transaction in Own Shares
21/02/2008       Director/PDMR Shareholding
21/02/2008       Director/PDMR Shareholding
21/02/2008       Director/PDMR Shareholding
21/02/2008       Director/PDMR Shareholding
21/02/2008       Transaction in Own Shares
20/02/2008       Director/PDMR Shareholding
20/02/2008       Transaction in Own Shares
20/02/2008       Director/PDMR Shareholding
20/02/2008       Director/PDMR Shareholding
19/02/2008       Director/PDMR Shareholding
19/02/2008       Transaction in Own Shares
18/02/2008       Director/PDMR Shareholding
18/02/2008       Transaction in Own Shares
15/02/2008       Transaction in Own Shares
14/02/2008       Director/PDMR Shareholding
14/02/2008       Director/PDMR Shareholding
14/02/2008       Transaction in Own Shares
13/02/2008       Transaction in Own Shares
12/02/2008       Director/PDMR Shareholding
12/02/2008       Director/PDMR Shareholding
12/02/2008       Transaction in Own Shares
12/02/2008       Transaction in Own Shares
08/02/2008        Director/PDMR Shareholding
07/02/2008        Final Results
04/02/2008        Director Declaration
01/02/2008        Total Voting Rights
28/01/2008        Director/PDMR Shareholding
23/01/2008        Director/PDMR Shareholding
17/01/2008        Director/PDMR Shareholding
17/01/2008        Director/PDMR Shareholding
17/01/2008        Director/PDMR Shareholding
16/01/2008        Director/PDMR Shareholding
16/01/2008        Director/PDMR Shareholding
16/01/2008        Director/PDMR Shareholding
15/01/2008        Director/PDMR Shareholding
14/01/2008        Director/PDMR Shareholding
14/01/2008        Director/PDMR Shareholding
14/01/2008        Director/PDMR Shareholding
14/01/2008        Director/PDMR Shareholding
11/01/2008        Director/PDMR Shareholding
03/01/2008        Director/PDMR Shareholding
03/01/2008        Director/PDMR Shareholding
02/01/2008        Director/PDMR Shareholding
02/01/2008        Director/PDMR Shareholding
02/01/2008        Total Voting Rights
19/12/2007        Director/PDMR Shareholding
18/12/2007        Holding(s) in Company
17/12/2007        CERVARIX -FDA Response Letter
17/12/2007        Director/PDMR Shareholding
14/12/2007        Tyverb -Positive EMEA Opinion
13/12/2007        Neuroscience Pipeline
13/12/2007        Transaction in Own Shares
12/12/2007        Director/PDMR Shareholding
12/12/2007        Transaction in Own Shares
11/12/2007        Transaction in Own Shares
10/12/2007        Transaction in Own Shares
07/12/2007        Board Committee Change
07/12/2007        Director/PDMR Shareholding
07/12/2007        Directorate Change
07/12/2007        Transaction in Own Shares
06/12/2007        Transaction in Own Shares
05/12/2007        Director/PDMR Shareholding
05/12/2007        Holding(s) in Company
05/12/2007        Transaction in Own Shares
04/12/2007        Director/PDMR Shareholding
04/12/2007        Holding(s) in Company
04/12/2007        Transaction in Own Shares
03/12/2007        Holding(s) in Company
03/12/2007        Total Voting Rights
03/12/2007        Transaction in Own Shares
30/11/2007        Director/PDMR Shareholding
30/11/2007        Transaction in Own Shares
29/11/2007        Transaction in Own Shares
28/11/2007        Director/PDMR Shareholding
28/11/2007        Transaction in Own Shares
27/11/2007        Transaction in Own Shares
26/11/2007        Holding(s) in Company
26/11/2007        Transaction in Own Shares
23/11/2007        Transaction in Own Shares
22/11/2007        Transaction in Own Shares
21/11/2007        Acquisition of Reliant Pharma
21/11/2007        Director/PDMR Shareholding
21/11/2007        Transaction in Own Shares
20/11/2007        Transaction in Own Shares
19/11/2007        Transaction in Own Shares
16/11/2007        Transaction in Own Shares-Amd
16/11/2007        Transaction in Own Shares
15/11/2007        Transaction in Own Shares
14/11/2007        Transaction in Own Shares
14/11/2007        US Labelling for Avandia
13/11/2007        Transaction in Own Shares
12/11/2007        Director/PDMR Shareholding
12/11/2007        Transaction in Own Shares
09/11/2007        Transaction in Own Shares
08/11/2007        Blocklisting Interim Review
08/11/2007        Transaction in Own Shares
07/11/2007        Transaction in Own Shares
06/11/2007        Transaction in Own Shares
06/11/2007        Transaction in Own Shares
05/11/2007        Transaction in Own Shares
02/11/2007        Additional Listing
02/11/2007        Director/PDMR Shareholding
02/11/2007        Total Voting Rights
02/11/2007        Transaction in Own Shares
01/11/2007        Transaction in Own Shares
31/10/2007        Transaction in Own Shares
30/10/2007        Transaction in Own Shares
29/10/2007        Transaction in Own Shares
29/10/2007        Transaction in Own Shares
26/10/2007        Transaction in Own Shares
25/10/2007        Director/PDMR Shareholding
25/10/2007        Transaction in Own Shares
24/10/2007        3rd Quarter Results
24/10/2007        Transaction in Own Shares
23/10/2007        Director/PDMR Shareholding
23/10/2007        Transaction in Own Shares
22/10/2007        Transaction in Own Shares
19/10/2007        Transaction in Own Shares
18/10/2007        Transaction in Own Shares
17/10/2007        Director/PDMR Shareholding
17/10/2007        Director/PDMR Shareholding
17/10/2007        Director/PDMR Shareholding
17/10/2007        Director/PDMR Shareholding
17/10/2007        Transaction in Own Shares
16/10/2007        Director/PDMR Shareholding
16/10/2007        Transaction in Own Shares
15/10/2007        Director/PDMR Shareholding
15/10/2007        Transaction in Own Shares
12/10/2007        Director/PDMR Shareholding
12/10/2007        Director/PDMR Shareholding
12/10/2007        Director/PDMR Shareholding
12/10/2007        Transaction in Own Shares
11/10/2007        Transaction in Own Shares
10/10/2007        Director/PDMR Shareholding
10/10/2007        Transaction in Own Shares
09/10/2007        Director/PDMR Shareholding
09/10/2007        Transaction in Own Shares
08/10/2007        CEO Designate
08/10/2007        Transaction in Own Shares
05/10/2007        Director Declaration
05/10/2007        Transaction in Own Shares
04/10/2007        Transaction in Own Shares
03/10/2007        Transaction in Own Shares
02/10/2007        Director/PDMR Shareholding
02/10/2007        Director/PDMR Shareholding
02/10/2007        Total Voting Rights
02/10/2007        Transaction in Own Shares
01/10/2007        Transaction in Own Shares
28/09/2007        Buy Back Programme
28/09/2007        Directorate Change
28/09/2007        Transaction in Own Shares
27/09/2007        Transaction in Own Shares
26/09/2007        Director/PDMR Shareholding
26/09/2007        Transaction in Own Shares
25/09/2007        Director/PDMR Shareholding
25/09/2007        Transaction in Own Shares
24/09/2007        Transaction in Own Shares
21/09/2007        Transaction in Own Shares
20/09/2007        Transaction in Own Shares
19/09/2007        Transaction in Own Shares
18/09/2007        Transaction in Own Shares
17/09/2007        Transaction in Own Shares
14/09/2007        Transaction in Own Shares
13/09/2007        Transaction in Own Shares
12/09/2007        Director/PDMR Shareholding
12/09/2007        Director/PDMR Shareholding
12/09/2007        Transaction in Own Shares
11/09/2007        Additional Listing
11/09/2007        Transaction in Own Shares
10/09/2007        Transaction in Own Shares
07/09/2007        Transaction in Own Shares
06/09/2007        Transaction in Own Shares
05/09/2007        Transaction in Own Shares
04/09/2007        Transaction in Own Shares
03/09/2007        Total Voting Rights
03/09/2007        Transaction in Own Shares
31/08/2007        Transaction in Own Shares
30/08/2007        Transaction in Own Shares
29/08/2007        Transaction in Own Shares
28/08/2007        Director/PDMR Shareholding
28/08/2007        Transaction in Own Shares
24/08/2007        Transaction in Own Shares
23/08/2007        Transaction in Own Shares
21/08/2007        Transaction in Own Shares
20/08/2007        Trans. in Own Shares-Amend
20/08/2007        Transaction in Own Shares
17/08/2007        Transaction in Own Shares
16/08/2007        Transaction in Own Shares
15/08/2007        Transaction in Own Shares
14/08/2007        Transaction in Own Shares
13/08/2007        Director/PDMR Shareholding
13/08/2007        Transaction in Own Shares
10/08/2007        Director/PDMR Shareholding
10/08/2007        Transaction in Own Shares
09/08/2007        Director/PDMR Shareholding
09/08/2007        Transaction in Own Shares
08/08/2007        Transaction in Own Shares
07/08/2007        Director/PDMR Shareholding
07/08/2007        Director/PDMR Shareholding
07/08/2007        Director/PDMR Shareholding
07/08/2007        Transaction in Own Shares
06/08/2007        Transaction in Own Shares
03/08/2007        Transaction in Own Shares
02/08/2007        Transaction in Own Shares-Amd
02/08/2007        Transaction in Own Shares-Amd
02/08/2007        Transaction in Own Shares
02/08/2007        Trexima FDA Approvable Letter
01/08/2007        Total Voting Rights
01/08/2007        Transaction in Own Shares
31/07/2007        Director/PDMR Shareholding
31/07/2007        FDA Ad Committee - Avandia
31/07/2007        Transaction in Own Shares
30/07/2007        Director/PDMR Shareholding
30/07/2007        Interim Report
27/07/2007        Director/PDMR Shareholding
25/07/2007        2nd Quarter Results
19/07/2007        Cervarix positive opinion
17/07/2007        Director/PDMR Shareholding
16/07/2007        Director/PDMR Shareholding
16/07/2007        Director/PDMR Shareholding
16/07/2007        Director/PDMR Shareholding
16/07/2007        Director/PDMR Shareholding
16/07/2007        Director/PDMR Shareholding
13/07/2007        Director/PDMR Shareholding
13/07/2007        Director/PDMR Shareholding
13/07/2007        Director/PDMR Shareholding
13/07/2007        Director/PDMR Shareholding
11/07/2007        Director/PDMR Shareholding
03/07/2007        Director/PDMR Shareholding
03/07/2007        Director/PDMR Shareholding
03/07/2007        Total Voting Rights
02/07/2007        Director/PDMR Shareholding
28/06/2007        Director/PDMR Shareholding
28/06/2007        Transaction in Own Shares
27/06/2007        Transaction in Own Shares
26/06/2007        Transaction in Own Shares
25/06/2007        Transaction in Own Shares
22/06/2007        Transaction in Own Shares
21/06/2007        Transaction in Own Shares
20/06/2007        Transaction in Own Shares
19/06/2007        Transaction in Own Shares
18/06/2007        Director/PDMR Shareholding
18/06/2007        Transaction in Own Shares
15/06/2007        Holding(s) in Company
15/06/2007        Transaction in Own Shares
14/06/2007        Transaction in Own Shares
13/06/2007        Transaction in Own Shares
12/06/2007        Director/PDMR Shareholding
12/06/2007        Transaction in Own Shares
11/06/2007        Transaction in Own Shares
08/06/2007        Transaction in Own Shares
07/06/2007        Transaction in Own Shares
06/06/2007        Interim data - RECORD study
04/06/2007        Director/PDMR Shareholding
01/06/2007        Total Voting Rights
30/05/2007        AGM - Special Business
29/05/2007        Transaction in Own Shares
24/05/2007        Transaction in Own Shares
23/05/2007        Result of AGM
23/05/2007        Transaction in Own Shares
22/05/2007        Transaction in Own Shares
21/05/2007        Director/PDMR Shareholding
21/05/2007        GSK responds to NEJM
18/05/2007        Transaction in Own Shares
16/05/2007        Transaction in Own Shares
14/05/2007        Transaction in Own Shares
11/05/2007        Director/PDMR Shareholding
10/05/2007        Transaction in Own Shares
09/05/2007        Director/PDMR Shareholding
09/05/2007        Director/PDMR Shareholding
09/05/2007        Transaction in Own Shares
08/05/2007        Transaction in Own Shares
03/05/2007        Transaction in Own Shares
02/05/2007        Total Voting Rights
02/05/2007        Transaction in Own Shares
30/04/2007        FDA Approval Veramyst
26/04/2007        Transaction in Own Shares
25/04/2007        1st Quarter Results
25/04/2007        Director/PDMR Shareholding
25/04/2007        Transaction in Own Shares
24/04/2007        Director/PDMR Shareholding
24/04/2007        Transaction in Own Shares
23/04/2007        Transaction in Own Shares
20/04/2007        Director/PDMR Shareholding
20/04/2007        Transaction in Own Shares
19/04/2007        Transaction in Own Shares
18/04/2007        Transaction in Own Shares
17/04/2007        Director/PDMR Shareholding
17/04/2007        Director/PDMR Shareholding
17/04/2007        Director/PDMR Shareholding
17/04/2007        Director/PDMR Shareholding
17/04/2007        Transaction in Own Shares
16/04/2007        Director/PDMR Shareholding
16/04/2007        Director/PDMR Shareholding
16/04/2007        Director/PDMR Shareholding
16/04/2007        Director/PDMR Shareholding
16/04/2007        Transaction in Own Shares
13/04/2007        Director/PDMR Shareholding
13/04/2007        Director/PDMR Shareholding
13/04/2007        Director/PDMR Shareholding
13/04/2007        Transaction in Own Shares
13/04/2007        Transaction in Own Shares
12/04/2007        Transaction in Own Shares
11/04/2007        Director/PDMR Shareholding
11/04/2007        Transaction in Own Shares
10/04/2007        Transaction in Own Shares
05/04/2007        Director/PDMR Shareholding
05/04/2007        Director/PDMR Shareholding
05/04/2007        Transaction in Own Shares
04/04/2007        Director/PDMR Shareholding
04/04/2007        Director/PDMR Shareholding
04/04/2007        Transaction in Own Shares
03/04/2007        Director/PDMR Shareholding
03/04/2007        Director/PDMR Shareholding
03/04/2007        Director/PDMR Shareholding
03/04/2007        Transaction in Own Shares
02/04/2007        Director/PDMR Shareholding
02/04/2007        Director/PDMR Shareholding
02/04/2007        Total Voting Rights
02/04/2007        Transaction in Own Shares
30/03/2007        Annual Information Update
30/03/2007        Buy-Back Programme
30/03/2007        Cervarix US Filing
30/03/2007        Director/PDMR Shareholding
30/03/2007        Director/PDMR Shareholding
30/03/2007        Transaction in Own Shares
29/03/2007        Transaction in Own Shares
28/03/2007        Director/PDMR Shareholding
28/03/2007        Director/PDMR Shareholding
28/03/2007        Director/PDMR Shareholding
28/03/2007        Transaction in Own Shares


2.      Documents filed at Companies House

All documents listed below were filed with the Registrar of Companies in England and Wales on or around the dates 
indicated, and can be obtained from Companies House via their website www.companieshouse.gov.uk

Date           Document Type  Description of Document Filed
17/03/2008     169            Return by a company purchasing its own shares
14/03/2008     88(2)          Return of Allotment of Shares
14/03/2008     88(2)          Return of Allotment of Shares
14/03/2008     88(2)          Return of Allotment of Shares
04/03/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
25/02/2008     88(2)          Return of Allotment of Shares
19/02/2008     88(2)R         Return of Allotment of Shares
18/02/2008     288a           Appointment of Director
18/02/2008     288a           Appointment of Director
14/02/2008     88(2)R         Return of Allotment of Shares
14/02/2008     88(2)R         Return of Allotment of Shares
14/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
11/02/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
31/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     169            Return by a company purchasing its own shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
24/01/2008     88(2)R         Return of Allotment of Shares
23/01/2008     88(2)R         Return of Allotment of Shares
15/01/2008     88(2)R         Return of Allotment of Shares
15/01/2008     88(2)R         Return of Allotment of Shares
15/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
10/01/2008     88(2)R         Return of Allotment of Shares
28/12/2007     88(2)R         Return of Allotment of Shares
28/12/2007     88(2)R         Return of Allotment of Shares
28/12/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
19/12/2007     88(2)R         Return of Allotment of Shares
19/12/2007     88(2)R         Return of Allotment of Shares
19/12/2007     88(2)R         Return of Allotment of Shares
19/12/2007     88(2)R         Return of Allotment of Shares
19/12/2007     88(2)R         Return of Allotment of Shares
19/12/2007     88(2)R         Return of Allotment of Shares
11/12/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
30/11/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
27/11/2007     88(2)R         Return of Allotment of Shares
12/11/2007     88(2)R         Return of Allotment of Shares
12/11/2007     88(2)R         Return of Allotment of Shares
12/11/2007     88(2)R         Return of Allotment of Shares
12/11/2007     88(2)R         Return of Allotment of Shares
12/11/2007     88(2)R         Return of Allotment of Shares
07/11/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
07/11/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
06/11/2007     88(2)R         Return of Allotment of Shares
05/11/2007     88(2)R         Return of Allotment of Shares
05/11/2007     88(2)R         Return of Allotment of Shares
05/11/2007     88(2)R         Return of Allotment of Shares
05/11/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
25/10/2007     88(2)R         Return of Allotment of Shares
24/10/2007     363a           Annual Return
24/10/2007     353            Location of Register of Members
11/10/2007     288a           Appointment of Director
10/10/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
08/10/2007     88(2)R         Return of Allotment of Shares
03/10/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
01/10/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
26/09/2007     88(2)R         Return of Allotment of Shares
26/09/2007     88(2)R         Return of Allotment of Shares
26/09/2007     88(2)R         Return of Allotment of Shares
26/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
18/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
11/09/2007     88(2)R         Return of Allotment of Shares
10/09/2007     88(2)R         Return of Allotment of Shares
07/09/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
03/09/2007     88(2)R         Return of Allotment of Shares
03/09/2007     88(2)R         Return of Allotment of Shares
03/09/2007     88(2)R         Return of Allotment of Shares
03/09/2007     88(2)R         Return of Allotment of Shares
03/09/2007     88(2)R         Return of Allotment of Shares
23/08/2007     88(2)R         Return of Allotment of Shares
23/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
15/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
07/08/2007     88(2)R         Return of Allotment of Shares
31/07/2007     88(2)R         Return of Allotment of Shares
31/07/2007     88(2)R         Return of Allotment of Shares
17/07/2007     88(2)R         Return of Allotment of Shares
17/07/2007     88(2)R         Return of Allotment of Shares
17/07/2007     88(2)R         Return of Allotment of Shares
17/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
13/07/2007     88(2)R         Return of Allotment of Shares
12/07/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
05/07/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
26/06/2007     88(2)R         Return of Allotment of Shares
15/06/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
15/06/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
15/06/2007     88(2)R         Return of Allotment of Shares
15/06/2007     88(2)R         Return of Allotment of Shares
15/06/2007     88(2)R         Return of Allotment of Shares
12/06/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
11/06/2007     RES 11         Amendment to the Articles and Memorandum of Association
07/06/2007     88(2)R         Return of Allotment of Shares
07/06/2007     88(2)R         Return of Allotment of Shares
07/06/2007     88(2)R         Return of Allotment of Shares
07/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
06/06/2007     88(2)R         Return of Allotment of Shares
29/05/2007     88(2)R         Return of Allotment of Shares
22/05/2007     88(2)R         Return of Allotment of Shares
21/05/2007     169            Return by a company purchasing its own shares
16/05/2007     88(2)R         Return of Allotment of Shares
16/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
15/05/2007     88(2)R         Return of Allotment of Shares
11/05/2007     288c           Change of Particulars of Director
10/05/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
04/05/2007     AA             Group of companies' accounts made up to 31/12/06
03/05/2007     169            Return by a company purchasing its own shares
26/04/2007     88(2)R         Return of Allotment of Shares
19/04/2007     88(2)R         Return of Allotment of Shares
19/04/2007     88(2)R         Return of Allotment of Shares
18/04/2007     AA             Directors' Report and Accounts
13/04/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
13/04/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
13/04/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
13/04/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
13/04/2007     88(2)R         Return of Allotment of Shares
13/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
12/04/2007     88(2)R         Return of Allotment of Shares
30/03/2007     169(1B)        Return by a public company purchasing its own shares for holding in treasury
29/03/2007     288a           New director appointed


3.                         Documents filed with the Securities and Exchange Commission ("SEC")

The Company submitted filings to the SEC in compliance with its obligations under national laws and rules dealing with 
the regulation of securities, issuers of securities and securities markets  by virtue of having American Depository 
Shares admitted to trading on the New York Stock Exchange. Full details of these filings can be found on the SEC's 
website at www.sec.gov.


4.      Documents sent to shareholders

The following documents were published and sent to shareholders. They are available on the Company's website.

Date of Publication                Document
28/02/2008                         Annual Report and Accounts
28/02/2008                         Annual Review
19/03/2008                         Notice of Annual General Meeting

A copy of this Annual Information Update and copies of the documents referred to in it can be obtained from the Deputy 
Company Secretary at the Company's registered office:

Victoria Whyte
Deputy Company Secretary
GlaxoSmithKline plc
980 Great West Road
Brentford
Middlesex
TW8 9GS

Tel: [phone]


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