Director/PDMR Shareholding

GlaxoSmithKline PLC
20 January 2006

   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned persons on 19 January 2006 of an increase in
their interests in Ordinary Shares at a price of £14.67 per share following the
re-investment of the dividend paid to shareholders on 5 January 2006:-

Mr R Bondy                                                        179
Mr M Dunoyer                                                       66
Dr D Pulman                                                       102
Mr A Witty                                                         62
Mrs J Younger                                                     158


This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).

S M Bicknell
Company Secretary

20 January 2006


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