Director/PDMR Shareholding

GlaxoSmithKline PLC 24 May 2006 Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons I give below details of changes in the interests of Directors, Persons Discharging Managerial Responsibility or Connected Persons in the Ordinary Shares of GlaxoSmithKline plc. 16 May 2006 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust") notified the Company on 24 May 2006 that 1,478 Ordinary shares in the Company had been sold on 16 May 2006 on behalf of participants in the GlaxoSmithKline Annual Investment Plan at a price of £15.23 per share. 16 May 2006 The Trust notified the Company on 24 May 2006 that 1,777 Ordinary shares in the Company had been transferred on 16 May 2006 from the Trust to a participant in the GlaxoSmithKline Annual Ivestment Plan. 17 May 2006 The Trust notified the Company on 24 May 2006 that 465 Ordinary shares in the Company had been sold on 17 May 2006 on behalf of participants in the GlaxoSmithKline Bonus Investment Plan at a price of £15.41 per share. 17 May 2006 The Trust notified the Company on 24 May 2006 that 664 Ordinary shares in the Company had been transferred on 17 May 2006 from the Trust to a participant in the GlaxoSmithKline Bonus Investment Plan. 18 May 2006 The Trust notified the Company on 24 May 2006 that 1,616 Ordinary shares in the Company had been sold on 18 May 2006 on behalf of participants in the GlaxoSmithKline Annual Investment Plan at a price of £15.05 per share. 18 May 2006 The Trust notified the Company on 24 May 2006 that 2,252 Ordinary shares in the Company had been transferred on 18 May 2006 from the Trust to a participant in the GlaxoSmithKline Annual Investment Plan. The Trust is a discretionary fund of which all non US employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Mr J Heslop is therefore interested in the shares held in the fund from time to time in the same way as other non US employees or former employees of GlaxoSmithKline plc and its subsidiaries. This notification relates to a transaction notified in accordance with Disclosure Rule 3.1.4R(1)(b). S M Bicknell Company Secretary 24 May 2006 This information is provided by RNS The company news service from the London Stock Exchange

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