Director/PDMR Shareholding

GlaxoSmithKline PLC
20 June 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary shares of
GlaxoSmithKline plc in respect of the under-mentioned Person Discharging
Managerial Responsibility:-
                    
Mrs J Younger       Exercise of options on 20 June 2006 over 46,700 
                    Ordinary shares granted on 25 February 2000 under 
                    the Glaxo Wellcome 1999 Share Option Plan at a 
                    price of £14.60 per share.

                    The sale of 46,700 shares on 20 June 2006 at an 
                    average price of £14.77.

                    The Company was advised of these transactions on 
                    20 June 2006.

These notifications are in accordance with Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

20 June 2006


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