Director/PDMR Shareholding

GlaxoSmithKline PLC
12 February 2008


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 12 February 2008 of an increase in the
notional allocation of Ordinary Share ADRs on 8 February 2008 at a price of
$42.16 per ADR:-

Dr J P Garnier                             130
Dr M Slaoui                                 13
Dr R G Greig                                34
Mr W C Louv                                  7
Dr D Pulman                                  9
Mr D M Stout                                62
Mr C Viehbacher                             14


This notification relates to a transaction notified in accordance with
Disclosure and Transparency Rule 3.1.4R(1)(a).

S M Bicknell
Company Secretary

12 February 2008


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