Director/PDMR Shareholding

GlaxoSmithKline PLC
21 May 2007



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 21 May 2007 of:

(i)  An increase in the notional allocation of Ordinary Share ADRs on 18 May
2007 at a price of $57.71 per share:-

Mrs C Bruck Slaoui           2
Dr R G Greig                 2

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell
Company Secretary


21 May 2007




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