Director/PDMR Shareholding

GlaxoSmithKline PLC 01 August 2006 Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons I give below details of changes in the interests of Directors, Persons Discharging Managerial Responsibility or Connected Persons in the Ordinary Shares of GlaxoSmithKline plc. 24 July 2006 The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust") notified the Company on 31 July 2006 that 433 Ordinary shares in the Company had been sold on 24 July 2006 on behalf of participants in the GlaxoSmithKline Bonus Investment Plan at a price of £14.87 per share. 24 July 2006 The Trust notified the Company on 31 July 2006 that 9,505 Ordinary shares in the Company had been sold on 24 July 2006 on behalf of participants in the GlaxoSmithKline Bonus Investment Plan at a price of £14.89 per share. 24 July 2006 The Trust notified the Company on 31 July 2006 that 69 Ordinary shares in the Company had been sold on 24 July 2006 on behalf of participants in the GlaxoSmithKline Bonus Investment Plan at a price of £15.06 per share. 24 July 2006 The Trust notified the Company on 31 July 2006 that 619 Ordinary shares in the Company had been transferred on 24 July 2006 from the Trust to a participant in the GlaxoSmithKline Bonus Investment Plan. The Trust is a discretionary fund of which all non US employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. One of the Company's directors, Mr J S Heslop is therefore interested in the shares held in the fund from time to time in the same way as other non US employees or former employees of GlaxoSmithKline plc and its subsidiaries. This notification relates to a transaction notified in accordance with Disclosure Rule 3.1.4R(1)(b). S M Bicknell Company Secretary 1 August 2006 This information is provided by RNS The company news service from the London Stock Exchange

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