Director Shareholding

GlaxoSmithKline PLC
18 July 2001

                             Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

17 July 2001         Abacus (GW) Trustees Limited, as trustee of The Glaxo      
                     Wellcome Employee Trust ('the Trust'), transferred         
                     896 Ordinary Shares in the Company to participants of the  
                     Glaxo Wellcome UK Share Option Scheme.


The Company was advised of this transaction on 18 July 2001.

The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe are therefore
interested in the shares held in the Trust from time to time in the same way
as other employees or former employees of Glaxo Wellcome plc and its
subsidiaries.


S M Bicknell

Company Secretary


18 July 2001