Director Shareholding

GlaxoSmithKline PLC
1 October 2001

                             Directors' Interests

I give below details of changes in the directors' interests in the Ordinary
Shares and ADS Shares of GlaxoSmithKline plc.

On 30 September 2001, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and American Depository
Shares (ADSs) in the Company under the automatic share allocation arrangements
for non-executive Directors for the period of service from 1 July to the 30
September 2001, as listed below.

Non Executive Director  Ordinary Shares     American Depository Shares (ADS)

Sir Richard Sykes            1,500
Sir Roger Hurn                750
Sir Peter Walters             750
Paul Allaire                                               125
Dr Michele Barzach            250
Sir Christopher Hogg          250
Sir Peter Job                 250
John McArthur                                              125
Donald McHenry                                             125
Sir Ian Prosser               250
Dr Ronaldo Schmitz            250
Dr Lucy Shapiro                                            125
John Young                                                 125

At the same time the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share election element of the share allocation arrangements for
non-executive Directors for the period of service from 1 July to the 30
September 2001, as listed below.

Non Executive Director  Ordinary Shares     American Depository Shares (ADS)

Sir Roger Hurn              532.4814
Sir Peter Walters           532.4814
Sir Peter Job               599.0415
John McArthur                                           163.4383
Sir Ian Prosser             299.5208
Dr Ronaldo Schmitz          292.8647
John Young                                              399.5157


The Company and the directors were informed of these allocations on 30
September 2001.


S M Bicknell

Company Secretary

1 October 2001