Director Shareholding

GlaxoSmithKline PLC
13 November 2001

                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.




The Administrators of the GlaxoSmithKline Retirement Savings Plan ('the Plan')
notified GlaxoSmithKline plc on 13 November 2001, that as a result of movements
in the fund: on 31 October 2001, the number of Ordinary Share ADRs held by the
fund increased by 65,021 at an average price of $53.300; and on 9 November 2001
the fund increased by a further 43,929 Ordinary Share ADRs at an average price
of $54.270. As at 13 November 2001 there were 18,544,813 shares in the Plan.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One
of the Company's directors, Dr J P Garnier is therefore, interested in the
shares held in the fund from time to time in the same way as other employees
or former employees of SmithKline Beecham plc and its subsidiaries.






S M Bicknell

Company Secretary


13 November 2001