Director Shareholding

GlaxoSmithKline PLC
20 March 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



15 March 2002                The Administrators of the SmithKline Beecham Employee Benefit Trust ("the Trust")
                             notified the Company on the 19 March 2002, that 140,147 Ordinary shares had been
                             transferred from the Trust to participants of the SmithKline Beecham 1991 Share
                             Option Plan.


The Trust is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.






S M Bicknell

Company Secretary


20 March 2002



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