Director Shareholding

GlaxoSmithKline PLC
18 February 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



15 February 2002   The Administrators of the SmithKline Beecham Employee 
                   Benefit Trust ('the Trust') notified the Company on the 18
                   February 2002, that 283,559 Ordinary shares had been
                   transferred from the Trust to participants of the SmithKline 
                   Beecham 1991 Share Option Plan and that 5,425 Ordinary shares 
                   had been transferred from the Trust to participants of the 
                   SmithKline Beecham Bonus Investment Plan.


The Trust is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.






S M Bicknell

Company Secretary


18 February 2002



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